Prediction of Postoperative Complications and Survival in Gastric Cancer Using Preoperative Blood Markers

NCT06686966 | Completed DMC

• 1 other identifier: ZZ2024-292-01
• Study Type: observational
• Target: 3,400
• Locations: 0 countries
• Sites: N/A

Brief Summary

Gastric cancer is one of the most common cancers worldwide, especially in East Asia. Although surgery remains the main treatment, patients may experience postoperative complications and have varying long-term survival outcomes. Early identification of high-risk patients before surgery is important for improving treatment decisions and patient management. This study aims to develop a prediction model based on routinely available preoperative blood test results and clinical characteristics to estimate the risk of postoperative complications and long-term survival in patients with gastric cancer. The model will be developed and validated using data from multiple medical centers. By using easily accessible clinical information, this study seeks to provide a practical tool to help clinicians better assess patient risk before surgery, support personalized treatment planning, and improve overall patient outcomes.

Conditions

Gastric Cancers

Keywords

gastric cancer; machine learning; serum biomarkers

Outcome Measures

Primary Outcomes (1)

• the incidence of gastric cancer

  the diagnosis time of gastric cancer

  From 18 years old until the developing gastric cancer, through study completion, an average of 5 year.

Interventions

gastric cancer DIAGNOSTIC_TEST

be diagnosed as gastric cancer

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with gastric cancer and undergoing radical gastric cancer surgery at the First Hospital of Chongqing Medical University, the Second Hospital of Chongqing Medical University, and the Yongchuan Hospital of Chongqing Medical University.

You may qualify if:

• patients aged ≥18 years;
• patients diagnosed with gastric cancer by pathological biopsy before surgery;
• patients without chemotherapy, radiotherapy, targeted and immunotherapy before enrolment;
• willing to participate in this study and sign the informed consent;
• complete clinical data.

You may not qualify if:

• patients with other primary malignant tumours other than gastric cancer;
• patients with systemic diseases such as severe cardiopulmonary insufficiency that affect the choice of treatment plan;
• patients who are not suitable for enrolment as assessed by the investigator;
• incomplete clinical data.

Sponsors & Collaborators

• First Affiliated Hospital of Chongqing Medical University: lead

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 12, 2024
• First Posted: November 13, 2024
• Study Start: January 1, 2010
• Primary Completion: November 1, 2024
• Study Completion: November 1, 2024
• Last Updated: March 3, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share