Relationship Between Grip Strength and Intraoperative Hemodynamic Parameters

NCT06679933 | Completed

• 1 other identifier: 2021-19/192
• Study Type: observational
• Target: 105
• Locations: 1 country
• Sites: 1

Brief Summary

In geriatric anesthesia, hand grip strength is used as an important biomarker to evaluate the general health status of elderly patients. Hand grip strength is considered an indicator of various factors, such as muscle function, physical endurance, nutritional status, and frailty, and can be helpful in geriatric anesthesia practice to predict patients' response to anesthesia and determine their risk. Hand grip strength is used as an important parameter in the pre-anesthesia evaluation of elderly patients. Low grip strength has been associated with postoperative complications (e.g., infection, pulmonary complications, prolonged hospitalization) and worse outcomes.Weak hand grip strength is related to the patient's degree of frailty. Frail patients may be less resistant to stress and respond more negatively to anesthesia. One of the most important of these responses is intraoperative hypotension, and it is especially common in elderly patients. Since hypotension has possible adverse effects in the postoperative period, it is necessary to evaluate elderly patients in more detail during the preoperative evaluation in order to predict this and take the necessary precautions. Hand grip strength has been found to be associated with cardiovascular system health. With this study, the investigators wanted to evaluate whether measuring hand grip strength during preoperative evaluation would help evaluate the risk of intraoperative hypotension.

Conditions

Hypotension During Surgery; Geriatric Patient; Hand Grip Strength

Keywords

Geriatric Anesthesia; Hang Grip Strength; Intraoperative Hypotension; Spinal Anesthesia

Outcome Measures

Primary Outcomes (1)

• Is low grip strength related with more hypotension?

  We examined whether low hand grip strength was associated with the frequency of intraoperative hypotension.

  During the surgery

Secondary Outcomes (1)

• Is there any difference in blood pressure changes between patients with low hand grip strength and patients with high hand grip strength.

  During the surgery

Interventions

Hand grip strength measurament OTHER

That intervention includes making the patient sit down and rest for 5 minutes on a comfortable chair. Then make them handle a hand dynamometer with their dominant hand and ask them to squeeze it with all of their effort. Repeat that squeeze three times with 2-minute intervals. The highest number recorded on the dynamometer is the hand grip strength of the patient.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Male and female patients over the age of 65 with an ASA score of 1-3 who underwent elective surgery in our hospital (Kırşehir Research and Education Hospital) were included in the study. Patients were selected and included in the study during preoperative evaluation at the anesthesia clinic.

You may qualify if:

• Patients who are 65 years and older
• Patients undergoing elective surgery
• Patients suitable for spinal anesthesia

You may not qualify if:

• Presence of anatomical or neurological dysfunction of the upper extremity
• Failed spinal anesthesia
• Failure to measure hand grip strength accurately

Sponsors & Collaborators

• Kirsehir Ahi Evran Universitesi: lead

Study Sites (1)

Kırşehir Ahi Evran University Research and Education Hospital

Kırşehir, Kırşehir, 40100, Turkey (Türkiye)

Location

Related Publications (2)

• Gregory A, Stapelfeldt WH, Khanna AK, Smischney NJ, Boero IJ, Chen Q, Stevens M, Shaw AD. Intraoperative Hypotension Is Associated With Adverse Clinical Outcomes After Noncardiac Surgery. Anesth Analg. 2021 Jun 1;132(6):1654-1665. doi: 10.1213/ANE.0000000000005250.

  PMID: 33177322 RESULT

• Carpenter RL, Caplan RA, Brown DL, Stephenson C, Wu R. Incidence and risk factors for side effects of spinal anesthesia. Anesthesiology. 1992 Jun;76(6):906-16. doi: 10.1097/00000542-199206000-00006.

  PMID: 1599111 RESULT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 4, 2024
• First Posted: November 8, 2024
• Study Start: January 1, 2022
• Primary Completion: January 1, 2023
• Study Completion: March 1, 2023
• Last Updated: November 8, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)