Comparison of Clinical Parameters in Chronic Obstructive Pulmonary Disease Patients and Healthy Individuals

NCT06677671 | Active Not Recruiting DMC

• 1 other identifier: AEŞH-BADEK-2024-553
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators think that the functions of core stabilization muscles are different in chronic obstructive pulmonary disease (COPD) patients than in healthy individuals. This muscle group plays an important role not only in stabilization but also in respiratory parameters. No study has been found investigating the functions of these muscles in this patient group. The investigators aimed to compare respiratory parameters, muscle parameters, exercise capacity, balance, quality of life, anxiety and depression levels in individuals with COPD and healthy individuals.

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Keywords

copd; exercise capacity; muscle parameters

Outcome Measures

Primary Outcomes (1)

• Cardiopulmonary exercise test

  Cardiopulmonary exercise test will be performed to evaluate the exercise capacity of the individuals who will participate in the study. During the test, individuals' respiratory and cardiac parameters will be recorded.

  September 2024, July 2026

Secondary Outcomes (9)

• Respiratory function

  September 2024, July 2026

• Respiratory muscle strength

  September 2024, July 2026

• Muscle activity and muscle thickness

  September 2024, July 2026

• COPD Assessment Questionnaire

  September 2024, July 2026

• Timed up and go test

  September 2024, July 2026

Study Arms (2)

Healthy

Healthy Individuals

COPD

Chronic Obstructive Pulmonary Disease Patients

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients and volunteer healthy individuals admitted to Ankara Etlik City Hospital

You may qualify if:

• Being diagnosed with COPD
• Being between the ages of 40-80
• Being clinically stable (not having had an exacerbation in the last month)
• Being able to cooperate with the tests
• Not participating in any exercise training studies
• Being willing to participate in the study
• Being between the ages of 40-80
• Not having a known acute or chronic health problem that would prevent the performance of the tests or affect the performance of the tests
• Not participating in any exercise training program
• Being willing to participate in the study

You may not qualify if:

• Having other lung or lung involvement diseases other than COPD
• Having uncontrolled hypertension, arrhythmia and a history of myocardial infarction in the last month, unstable angina, advanced heart failure and other cardiac instability conditions
• Being hemodynamically unstable
• Being on noninvasive mechanical ventilation (NIMV) and long-term oxygen therapy (LTOT)
• Having a history of neuromuscular disease, scoliosis, chest wall surgery
• Having pregnancy and malignancy
• Having orthopedic or surgical conditions that would prevent participation in tests
• Not willing to participate in the study
• Having a known acute or chronic health problem that would prevent the performance of the tests or affect the performance of the tests
• Being pregnant
• Not willing to participate in the study

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Ankara Etlik City Hospital

Ankara, 06170, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Week
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist, M.Sc

Study Record Dates

• First Submitted: November 3, 2024
• First Posted: November 7, 2024
• Study Start: September 1, 2024
• Primary Completion (Estimated): July 18, 2026
• Study Completion (Estimated): July 18, 2026
• Last Updated: November 7, 2024

Record last verified: 2024-11

Locations

TU (1)