Validation of a Questionnaire to Measure Cough Severity

NCT06669897 | Recruiting

• 1 other identifier: IIBSP-TOS-2023-133
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 6

Brief Summary

To design and validate a questionnaire that allows objective assessment of the severity of chronic cough

Conditions

Cough

Keywords

Cough; Chronic cough

Outcome Measures

Primary Outcomes (1)

• A questionnaire for assessing the severity of chronic cough

  To design and validate a questionnaire to objectively assess the severity of chronic cough

  1 year

Secondary Outcomes (1)

• Correlation of the results of the questionnaire with frequency of cough

  1 year

Study Arms (1)

Questionnaire

Chronic cough

Other: Questionnaire

Interventions

Questionnaire OTHER

Chronic cough questionnaire

Questionnaire

Eligibility Criteria

• Age: 30 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Spanish-speaking patients with previous diagnosis of chronic cough or healthy volunteers.

You may qualify if:

• Aged between 30 and 99 years
• Clinical diagnosis of chronic cough or healthy volunteers
• Good understanding of Spanish

You may not qualify if:

• Non-Spanish-speaking patients
• Inability to complete the questionnaires
• Failure to sign the informed consent form

Sponsors & Collaborators

• Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau: lead

Study Sites (6)

Hospital Universitario Hermanos Trias y Pujol

Badalona, Barcelona, 08916, Spain

ENROLLING BY INVITATION

Hospital Univesitario de Bellvitge

L'Hospitalet de Llobregat, Barcelona, 08907, Spain

RECRUITING

Parc Taulí Hospital Universitari

Sabadell, Barcelona, 08208, Spain

RECRUITING

Hospital del Mar

Barcelona, 08003, Spain

RECRUITING

Hospital Clínic de Barcelona

Barcelona, 08036, Spain

RECRUITING

Hospital de la Santa Creu i Sant Pau. Carrer Mas Casanovas 90.

Barcelona, 08041, Spain

RECRUITING

Related Publications (7)

• French CT, Irwin RS, Fletcher KE, Adams TM. Evaluation of a cough-specific quality-of-life questionnaire. Chest. 2002 Apr;121(4):1123-31. doi: 10.1378/chest.121.4.1123.

  PMID: 11948042 BACKGROUND

• McGarvey L, Gibson PG. What Is Chronic Cough? Terminology. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1711-1714. doi: 10.1016/j.jaip.2019.04.012. Epub 2019 Apr 17.

  PMID: 31002958 BACKGROUND

• Morice AH, McGarvey LP, Dicpinigaitis PV. Cough hypersensitivity syndrome is an important clinical concept: a pro/con debate. Lung. 2012 Feb;190(1):3-9. doi: 10.1007/s00408-011-9351-y. Epub 2011 Dec 22.

  PMID: 22186805 BACKGROUND

• Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest. 2005 May;127(5):1710-3. doi: 10.1378/chest.127.5.1710.

  PMID: 15888850 BACKGROUND

• Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S, Jo EJ, Kim MH, Plevkova J, Park HW, Cho SH, Morice AH. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J. 2015 May;45(5):1479-81. doi: 10.1183/09031936.00218714. Epub 2015 Feb 5. No abstract available.

  PMID: 25657027 BACKGROUND

• Morice A. Chronic cough: epidemiology. Chron Respir Dis. 2008;5(1):43-7. doi: 10.1177/1479972307084252.

  PMID: 18303101 BACKGROUND

• Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UBS, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Hammond CS, Tarlo SM. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 Suppl):1S-23S. doi: 10.1378/chest.129.1_suppl.1S. No abstract available.

  PMID: 16428686 BACKGROUND

MeSH Terms

Conditions

Cough; Chronic Cough

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Astrid Crespo-Lessmann, PhD

  Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Astrid Crespo-Lessmann, PhD

CONTACT

+34 93 556 56 01; acrespo@santpau.cat

Astrid Crespo, PhD

CONTACT

+34 93 556 56 01; acrespo@santpau.cat

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 31, 2024
• First Posted: November 1, 2024
• Study Start: May 1, 2025
• Primary Completion: November 1, 2025
• Study Completion: April 1, 2026
• Last Updated: September 15, 2025

Record last verified: 2024-10

Locations

ES (6)