Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT06669325 | Completed DMC

• 1 other identifier: PG-NMC/541/078-079
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis. The main questions it aims to answer are:

1. 1.Does Apfel's score accurately predict the occurrence of PONV after laparoscopic cholecystectomy?
2. 2.Which components of Apfel's score are most strongly associated with PONV?

Conditions

APFEL RİSK SCORE; Post Operative Nausea and Vomiting (PONV)

Outcome Measures

Primary Outcomes (1)

• Incidence of Postoperative Nausea and Vomiting (PONV)

  The number of patients who experience nausea and/or vomiting within 24 hours after laparoscopic cholecystectomy.

  Assessed for 24 hours post-surgery.

Secondary Outcomes (1)

• Relationship Between Apfel's Score and PONV Incidence

  Assessed for 24 hours post-surgery.

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of adult patients who are undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis. These patients are treated at the Department of General Surgery at National Medical College Teaching Hospital, Birgunj, Nepal.

You may qualify if:

• Patients aged 18 to 90 years.
• Patient scheduled for elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
• Patients who provided written informed consent to participate in the study.

You may not qualify if:

• Patients receiving prophylactic antiemetic medications prior to surgery.
• Patients on opioid analgesics for reasons other than the surgical procedure.
• Pregnant women.
• Patients whose laparoscopic cholecystectomy was converted to open cholecystectomy during the operation.

Sponsors & Collaborators

• National Medical College Birgunj: lead

Study Sites (1)

National Medical College and Teaching Hospital, Birgunj

Birgunj, Madesh, Nepal, Nepal

Location

MeSH Terms

Conditions

Vomiting

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: October 30, 2024
• First Posted: November 1, 2024
• Study Start: March 12, 2022
• Primary Completion: February 6, 2023
• Study Completion: October 28, 2023
• Last Updated: November 4, 2024

Record last verified: 2024-10

Locations

NE (1)