NCT06665581

Brief Summary

As a result of a longer life expectancy and a change in UV exposure, physicians will be facing a growing number of elderly patients with keratinocyte cancer (KC) in fair-skinned populations. The purpose of this study is to better characterize KC surgery in patients over 80 years and older with different comorbid conditions and to investigate the incidence of complications associated with KC surgery. A retrospective monocentric study of patients aged 80 and older, having surgery for KC in University Hospital of Zurich between January 1, 2022, and December 31, 2022, was conducted. Demographics, comorbidities, current medication, treatment type, tumor characteristics, surgical defect size, repair type and complications within 6 months after surgery were analyzed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
345

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2022

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2022

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 29, 2024

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 30, 2024

Completed
Last Updated

October 30, 2024

Status Verified

October 1, 2024

Enrollment Period

1.6 years

First QC Date

October 29, 2024

Last Update Submit

October 29, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incidence of complications associated with KC surgery in individuals aged 80 years and older

    From January 1, 2022, to December 31, 2022

Eligibility Criteria

Age80 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients aged 80 and older having surgery for KC in University Hospital of Zurich between January 1, 2022, and December 31, 2022. All patients included in the study were operated on by the same dermatologic surgery team of University Hospital of Zurich under local anesthe-sia

You may qualify if:

  • Patients aged 80 and older, having surgery for KC in University Hospital of Zurich between January 1, 2022, and December 31, 2022

You may not qualify if:

  • Presence of a documented rejection.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University Hospital Zurich, Dermatology Clinic

Zurich, Canton of Zurich, 8091, Switzerland

Location

University Hospital Zurich

Zurich, Canton of Zurich, 8091, Switzerland

Location

MeSH Terms

Conditions

Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
University Hospital Zurich

Study Record Dates

First Submitted

October 29, 2024

First Posted

October 30, 2024

Study Start

January 1, 2022

Primary Completion

August 1, 2023

Study Completion

August 1, 2024

Last Updated

October 30, 2024

Record last verified: 2024-10

Locations