Frequency and Impact of Iron Deficiency in Pain Clinic Patients

NCT06665516 | Completed

• 1 other identifier: BRID
• Study Type: observational
• Target: 81
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to measure the proportion of patients who have iron deficiency and if iron deficiency is treated what is the outcome. Participants will fill out a questionnaire to assess positive impact of iron supplementation treatment to assess whether they are at potential risk of iron deficiency

Conditions

Iron Deficiency; Fibromyalgia

Keywords

iron deficiency; fibromyalgia; iron infusion therapy; chronic pain; pain management; diet; sex and gender; women's health; serotonin

Outcome Measures

Primary Outcomes (1)

• Proportion of patients at risk of iron deficiency at the DeGroote Pain Clinic

  Our primary outcome is the proportion of the 81 patients who are at risk of iron deficiency. This will be measured through positive questionnaire responses with symptoms/conditions that indicate risk of iron deficiency. Women patients arriving for pain clinic visits will be asked if they wish to participate in this audit and complete a screening questionnaire.The questionnaire determines high risk for Iron Deficiency through known risk factors: heavy menstrual bleeding, previous iron status, and iron supplementation. Previous studies identified heavy menstrual bleeding as a significant predictor of anemia and progression into ID.7 Patients were asked to report any of the four major symptoms (need double sanitary protection, need to frequently change your protection, had or worried about flooding through to clothes or bedding, pass large blood clots.), with a yes to 2 or more being considered to describe heavy menstrual bleeding and therefore high risk for experiencing iron deficiency.

  from enrollment to end of treatment after 3 months

Eligibility Criteria

• Age: 18 Years - 49 Years
• Gender Eligibility Details: Cisgender women
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Female patients attending the DeGroote Pain Clinic

You may qualify if:

• Patient at the DeGroote Pain Clinic
• Menstruating women between the ages of 18-49
• Willingness to complete the questionnaire, and undergo laboratory tests if indicated.

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

DeGroote Pain Clinic

Hamilton, Ontario, L8S 4L8, Canada

Location

Related Publications (4)

• Murray CJL; GBD 2021 Collaborators. Findings from the Global Burden of Disease Study 2021. Lancet. 2024 May 18;403(10440):2259-2262. doi: 10.1016/S0140-6736(24)00769-4. No abstract available.

  PMID: 38762327 RESULT

• GBD 2021 Anaemia Collaborators. Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990-2021: findings from the Global Burden of Disease Study 2021. Lancet Haematol. 2023 Sep;10(9):e713-e734. doi: 10.1016/S2352-3026(23)00160-6. Epub 2023 Jul 31.

  PMID: 37536353 RESULT

• Pasricha SR, Tye-Din J, Muckenthaler MU, Swinkels DW. Iron deficiency. Lancet. 2021 Jan 16;397(10270):233-248. doi: 10.1016/S0140-6736(20)32594-0. Epub 2020 Dec 4.

  PMID: 33285139 RESULT

• Dugan C, MacLean B, Cabolis K, Abeysiri S, Khong A, Sajic M, Richards T; Women's Health research Collaborative. The misogyny of iron deficiency. Anaesthesia. 2021 Apr;76 Suppl 4:56-62. doi: 10.1111/anae.15432.

  PMID: 33682094 RESULT

Related Links

• This website provides a clear and concise summary of the information we will be investigating in this trial. This was provided to us by Dr. Toby Richards, the author of the website

MeSH Terms

Conditions

Iron Deficiencies; Fibromyalgia; Chronic Pain; Agnosia; Coitus

Condition Hierarchy (Ancestors)

Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Muscular Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Neuromuscular Diseases; Nervous System Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Perceptual Disorders; Neurobehavioral Manifestations; Sexual Behavior; Behavior

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 28, 2024
• First Posted: October 30, 2024
• Study Start: March 19, 2025
• Primary Completion: June 9, 2025
• Study Completion: June 9, 2025
• Last Updated: December 9, 2025

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)