Comparative Study Between Ultrasound Guided Quadratus Lumborum Versus Ilioingunial/ Iliohypogastric Nerves Block as Post-operative Analgesia for Patients Undergoing Inguinal Hernia Repair Surgeries

NCT06661707 | Not Yet Recruiting

• 1 other identifier: Ain Shams university S2
• Study Type: interventional
• Target: 44
• Locations: 0 countries
• Sites: N/A

Brief Summary

Postoperative pain management is becoming an integral part of anesthesia care. Various techniques of pain relief have been designed. We have designed the study for comparison between ultrasound guided quadratus lumborum (QL) block versus Ultrasound-guided ilioinguinal and iliohypogastric nerves (ILI+IHG) block as regard postoperative pain block and opioid consumption in patients undergoing inguinal hernia repair under general anesthesia.

Conditions

Post Operative Pain

Outcome Measures

Primary Outcomes (1)

• The time to the first request of analgesia

  visual analogue score ≥3 by giving pethidine (50 mg IV)

  24 hours postoperative

Secondary Outcomes (2)

• Total doses of analgesia

  24 hours postoperative

• occurence of side effects

  24 hours postoperative

Study Arms (2)

Quadratus Lumborum block (QL) group

ACTIVE COMPARATOR

Procedure: Sonar guided Quadratus Lumborum block

Ilioinguinal/Iliohypogastric block (ILI/IHG) group

ACTIVE COMPARATOR

Procedure: Sonar guided Ilioinguinal/Iliohypogastric block

Interventions

Sonar guided Quadratus Lumborum block PROCEDURE

The probe will be tilted down the lateral abdomen to identify a bright hyperechoic line that represents the middle layer of the thoracolumbar fascia. The needle will be inserted in plane from anterolateral to posteromedial. The needle tip will be placed between the thoracolumbar fascia and the QL muscle, and after negative aspiration, the correct position of the needle will be proved by injection of 5 mL of normal saline to confirm the space with a hypoechoic image and hydrodissection. An injection of (0.2 mL/kg of 0.25% bupivacaine per side) will be applied without exceeding the toxic dose 3 mg/kg

Quadratus Lumborum block (QL) group

Sonar guided Ilioinguinal/Iliohypogastric block PROCEDURE

The ultrasound linear probe will be placed over the anterior superior iliac spine with the superior margin of the transducer pointed directly in an oblique plane toward the umbilicus. The iliohypogastric nerve will be seen medial to the ilioinguinal nerve. The overlying skin will be prepared with antiseptic solution and 21 gauge 120mm Locoplex Sono Tap cannula will be advanced using an in-plane approach from a point just below the inferior border of the transducer toward the ilioinguinal nerve as it lies within the facial plane between the internal abdominal oblique and transverse abdominis muscles. After negative aspiration, (0.2 mL/kg of 0.25% bupivacaine per side) will be injected without exceeding the toxic dose of 3 mg/kg

Ilioinguinal/Iliohypogastric block (ILI/IHG) group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Physical Status: ASA (American society of Anesthesiologists) I - II patients.
• undergoing inguinal hernia repair

You may not qualify if:

• Contraindications to QL block \& ILI+IHG nerve block such as; (Infection at site of injection, allergy to local anesthetic drugs.)
• Refusal of procedure or participation in the study by patients.
• Psychiatric illness or uncooperative patient.
• Coagulopathy, use of anticoagulants or antiplatelet therapy.
• Chronic analgesic users, drug addicts and alcoholic patients.

Sponsors & Collaborators

• Ain Shams University: lead

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Anesthesia

Study Record Dates

• First Submitted: October 25, 2024
• First Posted: October 28, 2024
• Study Start: October 30, 2024
• Primary Completion: May 30, 2025
• Study Completion: May 30, 2025
• Last Updated: October 28, 2024

Record last verified: 2024-10