An Observational Clinical Study on the Construction of an Artificial Neural Network Model for ICU Pneumonia

NCT06661499 | Not Yet Recruiting

• 1 other identifier: 2024-607-01
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 1

Brief Summary

To achieve rapid, intelligent and accurate microbiological diagnosis and treatment for ICU pneumonia, an artificial neural network model for microbiological diagnosis is established, which depends on many clinical cases and machine deep learning from clinical experts' judgements according to species-specific rapid detection of pathogenic bacteria and other clinical parameter variables of patients.

Conditions

Pneumonia

Keywords

pneumonia; colonization; infection; artificial neural network model; intensive care unit

Outcome Measures

Primary Outcomes (1)

• clinical evaluation of each microbial detected whether in colonization or infection

  Two experienced senior physicians are organized to determine whether the microbial are colonized or infected according to clinical values.

  day1,day3 and day7 after enrollment

Interventions

establish an artificial neural network model OTHER

to establish an artificial neural network model for pathogen diagnosis in ICU pneumonia

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Pneumonia patients who admitted to Nanjing Drum Tower Hospital from Jan 1,2025 to Dec 31,2027 and meet the inclusion criteria.

You may qualify if:

• aged ≥18 years;
• agreed to obtain lower respiratory specimens for rapid testing of pathogenic bacteria;
• all were enrolled by an experienced physician who dynamically determined that the microorganisms were in a colonised or infected state;
• signed an informed consent form.

You may not qualify if:

• pregnant women;
• lactating women;
• patients who could not obtain lower respiratory specimens;

Sponsors & Collaborators

• Chinese Medical Association: lead

Study Sites (1)

Nanjing Drum Tower Hospital

Nanjing, Jiangsu, 210008, China

Location

MeSH Terms

Conditions

Pneumonia; Infections

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Yan Wang, Master

  Nanjing Drum Tower Hosptial

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Yan Wang, Master

CONTACT

+86 18905150275; a_nengneng@163.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2024
• First Posted: October 28, 2024
• Study Start: January 1, 2025
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: October 28, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)