NCT06661291

Brief Summary

Pip Care is developing a personalized, interactive surgical journey platform with a live health coach that works directly with health systems to optimize the perioperative care process. Our Health Insurance Portability and Accountability Act (HIPAA)-compliant platform, Pip, can be integrated into any electronic medical record (EMR), thus alleviating the administrative burden by making operational workflows more efficient. The PIP empowers patients and their families to be more involved in their care by breaking down a patient's healthcare plan into definable, easy-to-understand, and easy-to-complete tasks. Additionally, a health coach completes a health intake to create a personalized perioperative care plan, meets regularly with the patient to encourage goal accomplishment, and facilitates care coordination. This project has 2 phases; Phase I is to assess usability of the Pip Care platform in surgical patients, Phase II is a RCT (Randomized Controlled Trial) to assess surgical clinical outcomes while using Pip compared to standard of care.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,300

participants targeted

Target at P75+ for not_applicable

Timeline
28mo left

Started Oct 2025

Typical duration for not_applicable

Geographic Reach
1 country

8 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress20%
Oct 2025Sep 2028

First Submitted

Initial submission to the registry

October 24, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 28, 2024

Completed
12 months until next milestone

Study Start

First participant enrolled

October 13, 2025

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2028

Last Updated

October 28, 2025

Status Verified

October 1, 2025

Enrollment Period

2.9 years

First QC Date

October 24, 2024

Last Update Submit

October 24, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Length of Hospital Stay

    The total length of hospital stay (# of days) compared between study groups. Outcome will be reported as mean(SD).

    Up to 7 days following surgery

  • Hospital Readmission

    This outcome will be measured by the count of participants who experience hospital readmission following surgery in each study group.

    Up to 30 days following surgery

Secondary Outcomes (3)

  • Emergency Room Visits Post-Operatively

    Up to 30 days following surgery

  • Discharge to Long-term Care Facility

    Up to 30 days following surgery

  • Complication Rates

    Up to 30 days following surgery

Study Arms (2)

Pip Care Intervention Group

EXPERIMENTAL

Subjects randomized to the Pip Care Intervention group will receive access to the Pip Care digital health platform 1-week prior to their scheduled elective, inpatient surgery and retain access to the digital health platform for 30-days following surgery.

Other: Pip Care Digital Health Platform

Standard of Care Group

ACTIVE COMPARATOR

Subjects randomized to the standard of care group will receive routine standard of care for their planned elective, inpatient surgery.

Other: Standard of Care Protocol

Interventions

Pip Care Digital Health Platform is a smartphone application granting access to a health coach who will assist the patient in completing a health intake, creating personalized perioperative care plans, and meets regularly with the patient to encourage goal accomplishments and supports healthy surgical recovery.

Pip Care Intervention Group

Subjects in this intervention group will receive routine, standard of care throughout their surgery and hospital stay as determined by their acting clinical care team.

Standard of Care Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patient ≥18 years old
  • Planned elective, inpatient surgery between 2 to 8 weeks following enrollment in Pip within the following surgical specialties: complex abdominal surgery (general surgery, colorectal surgery, surgical oncology), gynecologic oncology, thoracic surgery, spine surgery, and orthopedic joint surgery
  • Daily access to a smartphone or tablet.

You may not qualify if:

  • Unable to speak English
  • Unable to use a smartphone or tablet independently or with daily assistance.
  • Currently pregnant (assessed via standard-of-care pre-operative workup)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

UPMC Jameson Hospital

New Castle, Pennsylvania, 16105, United States

RECRUITING

UPMC East Hospital

Pittsburgh, Pennsylvania, 15146, United States

RECRUITING

UPMC Horizon

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

UPMC Magee Womens Hospital

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

UPMC Presbyterian Hospital

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

UPMC St. Margaret

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

UPMC Shadyside Hospital

Pittsburgh, Pennsylvania, 15232, United States

RECRUITING

UPMC Passavant Hospital

Pittsburgh, Pennsylvania, 15237, United States

RECRUITING

Study Officials

  • Jennifer Holder-Murray, MD

    University of Pittsburgh, UPMC

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Carly Riedmann, MPH

CONTACT

Amy Monroe, MPH, MBA

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: A Randomized Clinical Trial to determine the effectiveness of Pip Care in improving clinical and patient reported outcomes when compared to standard perioperative care in 1300 subjects.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 24, 2024

First Posted

October 28, 2024

Study Start

October 13, 2025

Primary Completion (Estimated)

September 1, 2028

Study Completion (Estimated)

September 1, 2028

Last Updated

October 28, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will share

De-identified data may be shared with others inside and outside of the University who are conducting similar research. Though, at this time, there is no plan to share data with outside universities. De-identified data will be shared with PIP CARE INC.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data will become available as soon as it is retrieved per subject and will be available for 3.5 years (duration of the study enrollment and one year after for data analysis purposes)
Access Criteria
Access to trial IPD can be requested by qualified researchers engaging in independent scientific research and will be provided following review and approval of a research proposal and Statistical Analysis Plan (SAP) and execution of a Data Sharing Agreement (DSA).

Locations