NCT06656468

Brief Summary

Observational study aimed to evaluate the rate and of complications related to lealdless pacemaker implantation.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
900

participants targeted

Target at P75+ for all trials

Timeline
1mo left

Started Sep 2019

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress99%
Sep 2019Jun 2026

Study Start

First participant enrolled

September 1, 2019

Completed
5.1 years until next milestone

First Submitted

Initial submission to the registry

October 21, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 24, 2024

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Expected
Last Updated

October 24, 2024

Status Verified

October 1, 2024

Enrollment Period

6.3 years

First QC Date

October 21, 2024

Last Update Submit

October 22, 2024

Conditions

Keywords

Bradyarrhythmiasleadless pacemakercomplications

Outcome Measures

Primary Outcomes (1)

  • Acute complications

    Acute complications related to leadless pacemaker implantation

    From date of implantation until the date of first documented complication, assessed up to 30 days.

Secondary Outcomes (1)

  • Long-term complications

    From 31th day from implantation until the date of first documented complication, assessed up to 6 months.

Study Arms (1)

Leadless pacemaker patients

Consecutive patients undergoing leadless pacemaker patients

Device: Pacemaker and defibrillator

Interventions

Leadless pacemaker implantation procedure performed accordng to usual clinical practice. The indication for pacemaker implantation will be based on current guidelines.

Leadless pacemaker patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with indication for leadless pacemaker implantation for symptomatic bradyarrhythmias according to current Guidelines on cardiac pacing.

You may qualify if:

  • patients with indication for leadless pacemaker implantation according to current Guidelines on cardiac pacing.

You may not qualify if:

  • inability to sign informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Azienda Ospedaliera "Card. G. Panico"

Tricase, 73039, Italy

Location

Related Publications (1)

  • Palmisano P, Facchin D, Ziacchi M, Nigro G, Nicosia A, Bongiorni MG, Tomasi L, Rossi A, De Filippo P, Sgarito G, Verlato R, Di Silvestro M, Iacopino S. Rate and nature of complications with leadless transcatheter pacemakers compared with transvenous pacemakers: results from an Italian multicentre large population analysis. Europace. 2023 Feb 8;25(1):112-120. doi: 10.1093/europace/euac112.

    PMID: 36036679BACKGROUND

MeSH Terms

Conditions

Bradycardia

Interventions

Defibrillators

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

ElectrodesElectrical Equipment and SuppliesEquipment and Supplies

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

October 21, 2024

First Posted

October 24, 2024

Study Start

September 1, 2019

Primary Completion

December 31, 2025

Study Completion (Estimated)

June 1, 2026

Last Updated

October 24, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

Locations