NCT06656273

Brief Summary

The goal of this clinical trial is to learn whether a companion software application can improve program engagement in the National Diabetes Prevention Program in adults with prediabetes. The main question\[s\] it aims to answer \[is/are\]: Do participants using the software application (the intervention group) have better engagement with the Diabetes Prevention Program than those who do not use the companion software application (the control group)? Are participants using the software application (the intervention group) more likely to stay in the Diabetes Prevention Program longer than those who do not use the companion software application (the control group)? Participants are those who have signed up for their local Diabetes Prevention Program and agree to be in the study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
450

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2021

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 13, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 12, 2022

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

October 18, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 24, 2024

Completed
Last Updated

March 27, 2026

Status Verified

March 1, 2026

Enrollment Period

1.2 years

First QC Date

October 18, 2024

Last Update Submit

March 24, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Engagement as measured by number of classes attended by participant

    The primary measure for participant engagement will be the number of classes attended by a participant.

    From enrollment to end of the Lifestyle Change Program, up to 12 months.

  • Retention as measured by percentage of participants that remain enrolled at end of study

    The primary measure for retention will be the percentage of participants that remain enrolled in the LCP at the end of the study period.

    From enrollment to end of the Lifestyle Change Program, up to 12 months.

  • Efficacy as measured by the percentage of participants that achieve the goal of >/= 5% weight loss by end of study

    The primary measure of efficacy will be the percentage of participants who reach the LCP goal of ≥5% weight loss by the end of the study period.

    From enrollment to end of the Lifestyle Change Program, up to 12 months.

Study Arms (2)

FT LCP

EXPERIMENTAL
Behavioral: FT LCP

Standard LCP

NO INTERVENTION

Interventions

FT LCPBEHAVIORAL

FT LCP is a behavior change software application, used as an adjunct to the standard National Diabetes Prevention Program

FT LCP

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • is eligible for and enrolls in a live or distance LCP at a designated study site during the enrollment period of the study
  • has a smartphone or other device able to engage with the FT LCP app
  • can read basic 5th grade English, as used in the FT LCP app

You may not qualify if:

  • Cohorts and sites enrolled in concurrent, similar health app-based studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Institute of Iterative Thinking

Felton, California, 95018, United States

Location

Related Publications (1)

  • Leichter JW, Cannon MJ, Mensa-Wilmot Y, Belay ZW, Garza AS, Schmalz AM, Walch KI, Bobinet K. An iterative mindset approach as an adjunct to the national diabetes prevention program: a randomized trial assessing retention, engagement and weight loss. BMC Digit Health. 2026;4(1):13. doi: 10.1186/s44247-026-00247-y. Epub 2026 Feb 25.

MeSH Terms

Conditions

Prediabetic State

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 18, 2024

First Posted

October 24, 2024

Study Start

February 1, 2021

Primary Completion

April 13, 2022

Study Completion

October 12, 2022

Last Updated

March 27, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations