Effect of Kinetic Chain Exercises on Muscle Strength, Joint Position Sense and Quality of Life in Children with Haemophilia.

NCT06649175 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005128
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if there are effect of close kinetic chain exercises on muscle strength, joint position sense and Quality of life in children with haemophilia? Null hypothesis It will be hypothesized that: There is no effect of close kinetic chain exercises on muscle strength, joint position sense and Quality of life in children with haemophilia.

Conditions

Hemophilia a; Muscle Strength; Joint Position Sense; Quality of Life (QOL)

Outcome Measures

Primary Outcomes (1)

• a) Assessment of muscle strength:

  The isometric muscle strength of bilateral knee extensors muscles will be measured with a handheld dynamometer.

  baseline only

Secondary Outcomes (1)

• b) Assessment of knee joint position sense.

  baseline only

Other Outcomes (1)

• c) Assessment of Quality of life.

  baseline only

Study Arms (2)

group(A):exercise group.

ACTIVE COMPARATOR

Control Group (A): will receive the traditional physical therapy (PT) program for one hour two times weekly for six successive weeks. Intervention: traditional physical therapy program.

Other: Exercise

Group(B): modified exercise group.

ACTIVE COMPARATOR

Group (B): will receive a program of close kinetic chain exercises for 30 min.

Other: Exercise

Interventions

Exercise OTHER

Close kinetic chain (CKC) exercises : 1. Supine wall push exercise: Start position: supine with the both leg against wall, other limb straight. Exercise action: push against wall for thirty seconds. 2. Wall push against Swiss ball exercise: Start position: Supine with a Swiss ball between patient's legs and the wall. Exercise action: push against the wall for thirty seconds. 3. Supine half bridging exercise: Start position: Lying on back, knees bent Exercise action: keeping spine neutral and hinging up from the hips, move into a bridge.

Also known as: Close Kinetic Chain Exercise (CKC)

Group(B): modified exercise group.

Eligibility Criteria

• Age: 5 Years - 7 Years
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• \. Their chronological age will be 5-7yeasr. 2. All children will receive prophylaxis therapy. 3. They will able to stand and walk independently. 4. They will be able to follow instructions during evaluation and treatment.

You may not qualify if:

• The children will be excluded if they have one of the following:
• Visual or auditory problem.
• Radiographic changes as bone erosions, destruction, or joint subluxation, or congenital or acquired skeletal deformities in both lower limbs.
• Surgical procedures performed six weeks prior to or during study.
• Bleeding in joint 2 week prior to assessment.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Out Patient clinic of Atfal Misr hospital

Cairo, 4260044, Egypt

Location

MeSH Terms

Conditions

Hemophilia A

Interventions

Exercise

Condition Hierarchy (Ancestors)

Blood Coagulation Disorders, Inherited; Blood Coagulation Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Coagulation Protein Disorders; Hemorrhagic Disorders; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Central Study Contacts

YASMEIN EL-TANANY, M.Sc. in Physical Therapy

CONTACT

00201065080993; 10722018587060@pg.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: October 17, 2024
• First Posted: October 18, 2024
• Study Start: November 1, 2024
• Primary Completion: November 30, 2024
• Study Completion: March 1, 2025
• Last Updated: October 21, 2024

Record last verified: 2024-03

Locations

EG (1)