The Effect of Gait Training Using Different Slope Types on Balance in COPD Patients
The Effect of Aerobic Exercise Training at Different Slope Types on Balance in COPD Patients
1 other identifier
interventional
51
1 country
1
Brief Summary
Although COPD is basically a respiratory system disease, its effects are not limited to the respiratory system. In this context, one parameter affected in COPD patients is balance. Recent studies have highlighted the importance of assessing balance and incorporating it into treatment options such as pulmonary rehabilitation. In this context, we aim to diversify the training by using different slope types (downhill, level, uphill) in aerobic exercise training, which is a strong component of pulmonary rehabilitation, and to evaluate the effect of slope type on balance. Testing different types of inclines in aerobic exercise training has the potential to result in different muscular gains. We anticipate that this may result in different balance gains.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 15, 2024
CompletedFirst Posted
Study publicly available on registry
October 16, 2024
CompletedStudy Start
First participant enrolled
April 9, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2026
June 13, 2025
June 1, 2025
1.1 years
October 15, 2024
June 10, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Postural stability test
The test reflects a person's ability to maintain the center of balance.
Up to 8 weeks.
Limits of Stability (LOS) Test
The maximum vertical angle that the body can reach while standing without losing balance is called the stability limit.
Up to 8 weeks.
Clinical Test of Sensory Integration of Balance (CTSIB)
The test assesses how well the person can integrate sensory input to maintain balance.
Up to 8 weeks.
Study Arms (3)
Level walking
ACTIVE COMPARATORIt will walk at a 0-degree slope (0) throughout the research.
Downhill walking
EXPERIMENTALIt will walk at a 10-degree downhill slope (-10) throughout the research.
Uphill walking
EXPERIMENTALIt will walk at a 10-degree uphill slope (+10) throughout the research.
Interventions
For 8 weeks, level walking training will be done 2 times a week at a slope of 0 degrees.
For 8 weeks, downhill walking training will be done 2 times a week at a slope of -10 degrees.
For 8 weeks, uphill walking training will be done 2 times a week at a slope of +10 degrees.
Eligibility Criteria
You may qualify if:
- Being diagnosed with COPD (A, B, E groups according to GOLD assessment)
- Ambulate on your own
- Not having any contraindications for exercise
You may not qualify if:
- Being in GOLD 4 stage in spirometric evaluation
- Presence of hypoxemia
- Participation in another pulmonary rehabilitation program within the last 6 months
- Having an exacerbation in the last 1 month
- Being diagnosed with additional respiratory disease (asthma, bronchiectasis, etc.)
- Having had pulmonary surgery
- Having an orthopedic, neurological or cardiac disease that affects exercise
- Having uncontrolled hypertension or diabetes
- Presence of malignancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bezmialem Vakif University, Department of Physiotherapy and Rehabilitation
Istanbul, Eyüp Sultan, Turkey (Türkiye)
Related Publications (6)
Borghi-Silva A, Arena R, Castello V, Simoes RP, Martins LE, Catai AM, Costa D. Aerobic exercise training improves autonomic nervous control in patients with COPD. Respir Med. 2009 Oct;103(10):1503-10. doi: 10.1016/j.rmed.2009.04.015. Epub 2009 May 22.
PMID: 19464865BACKGROUNDLoughran KJ, Atkinson G, Beauchamp MK, Dixon J, Martin D, Rahim S, Harrison SL. Balance impairment in individuals with COPD: a systematic review with meta-analysis. Thorax. 2020 Jul;75(7):539-546. doi: 10.1136/thoraxjnl-2019-213608. Epub 2020 May 14.
PMID: 32409612BACKGROUNDKaygusuz MH, Oral Tapan O, Tapan U, Genc S. Balance impairment and cognitive dysfunction in patients with chronic obstructive pulmonary disease under 65 years. Clin Respir J. 2022 Mar;16(3):200-207. doi: 10.1111/crj.13469. Epub 2022 Jan 26.
PMID: 35081270BACKGROUNDJirange P, Vaishali K, Sinha MK, Bairapareddy KC, Alaparthi GK. A Cross-Sectional Study on Balance Deficits and Gait Deviations in COPD Patients. Can Respir J. 2021 Jan 6;2021:6675088. doi: 10.1155/2021/6675088. eCollection 2021.
PMID: 33505539BACKGROUNDEymir M, Yakut H, Ozalevli S, Alpaydin AO. Static and dynamic balance impairment and relationship with disease-related factors in patients with chronic obstructive pulmonary disease : A cross-sectional study. Wien Klin Wochenschr. 2021 Nov;133(21-22):1186-1194. doi: 10.1007/s00508-021-01918-8. Epub 2021 Aug 5.
PMID: 34351502BACKGROUNDAlexander N, Strutzenberger G, Ameshofer LM, Schwameder H. Lower limb joint work and joint work contribution during downhill and uphill walking at different inclinations. J Biomech. 2017 Aug 16;61:75-80. doi: 10.1016/j.jbiomech.2017.07.001. Epub 2017 Jul 11.
PMID: 28734544BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research Assistant
Study Record Dates
First Submitted
October 15, 2024
First Posted
October 16, 2024
Study Start
April 9, 2025
Primary Completion (Estimated)
June 1, 2026
Study Completion (Estimated)
June 1, 2026
Last Updated
June 13, 2025
Record last verified: 2025-06