The Effect of Cosmetic Face Care Products on Facial Skin Tone and Spot Brightening
A Clinical Study to Evaluate the Efficacy of Prototypes for Improvement in Skin Tone and Spot Brightening in a Full-Face Study Design
1 other identifier
interventional
250
1 country
1
Brief Summary
This is a single centre, 5-cell, blinded study to evaluate changes in even skin tone, skin glow, facial pigmented spots, and the microbiome of facial skin following the use of cosmetic face care products on the whole face over a 12 week period.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 10, 2024
CompletedFirst Posted
Study publicly available on registry
October 15, 2024
CompletedStudy Start
First participant enrolled
October 22, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 13, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
November 13, 2025
CompletedNovember 17, 2025
November 1, 2025
1.1 years
October 10, 2024
November 14, 2025
Conditions
Outcome Measures
Primary Outcomes (2)
Visual assessment of skin colour
0-12 weeks + 6 weeks regression
Instrumental assessment of skin colour
0-12 weeks + 6 weeks regression
Secondary Outcomes (1)
Changes in skin surface microbiome
0-12 weeks + 6 weeks regression
Other Outcomes (2)
Self assessment questionnaires
0-12 weeks + 6 weeks regression
Visual assessment of facial skin glow and radiance.
0-12 weeks + 6 weeks regression
Study Arms (5)
Cosmetic product G18
EXPERIMENTALCosmetic face care product to be used twice daily on the whole face for 12 weeks.
Cosmetic product N70
EXPERIMENTALCosmetic face care product to be used twice daily on the whole face for 12 weeks.
Cosmetic product D79
EXPERIMENTALCosmetic face care product to be used twice daily on the whole face for 12 weeks.
Cosmetic product E84
EXPERIMENTALCosmetic face care product to be used twice daily on the whole face for 12 weeks.
Cosmetic product C68
EXPERIMENTALCosmetic face care product to be used twice daily on the whole face for 12 weeks.
Interventions
To be used by all participants throughout the study
Eligibility Criteria
You may qualify if:
- Female adult participants in general good health as determined from a recent medical history.
- Participants in the age group of 20-45 years (both ages inclusive).
- Participants having Fitzpatrick photo-type III-V.
- Participants with at least 3 spots on the cheek either of PIH post acne/age related
- Participants not presenting any skin condition that may interfere with the assessment for the entire study duration.
- Participants free of excessive hair, acne, cuts, abrasions, fissures, wounds, lacerations, or any other active skin conditions on the face
- Participant who agrees not to use any other product/treatment/home remedy/serum on their face during the study period other than the study product.
- Participants who agree to remove all jewellery on/around face (e.g., necklace, earrings, nose ring), during imaging.
- Participants willing to give a voluntary written informed consent and photography release.
- Participants willing to abide by and comply with the study protocol.
- Participants able to read, understand and sign an appropriate informed consent form indicating her willingness to participate.
- Participants willing and capable to follow the study rules and a fixed schedule.
You may not qualify if:
- Participants who are currently participating in a similar study or have participated in a similar study in the past 6 weeks.
- Participants with any other signs of significant local irritation, erythema, or skin disease on skin.
- Participants having chronic illness or who have undergone major surgery in the last year that may be clinically relevant or can impact the results as determined by the dermatologist.
- Participants undergoing treatment for any skin condition.
- Participants allergic or sensitive to bar cleansing products, creams/lotions, artificial jewellery or anything else.
- Participants with self-perceived pimple prone and/or sensitive skin.
- Participants taking any oral antibiotic medication currently or within the last 8 weeks.
- Participants taking medication continuously/regularly every day such as corticosteroids or non-steroidal anti-inflammatories, topically for four weeks or orally for eight weeks prior to the study.
- Female participant pregnant/breast feeding or planning pregnancy during the study period (self-declared)
- Participants taking product/treatment for any condition which the Investigator believes may influence the interpretation of the data.
- Participants currently taking any medication, which the investigator believes may influence the interpretation of the data.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Unilever R&Dlead
- MS Clinical Research Pvt. Ltdcollaborator
Study Sites (1)
MS Clinical Research Pvt Ltd
Bangalore, 560008, India
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Masking Details
- Statistician
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 10, 2024
First Posted
October 15, 2024
Study Start
October 22, 2024
Primary Completion
November 13, 2025
Study Completion
November 13, 2025
Last Updated
November 17, 2025
Record last verified: 2025-11
Data Sharing
- IPD Sharing
- Will not share