Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections

NCT06638645 | Recruiting

• 1 other identifier: THE-2024-0246
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 2

Brief Summary

In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated. Currently, whenever possible, these anatomical lung resections are performed thoracoscopically, as they offer significant improvements in terms of postoperative pain, number of postoperative complications, rehabilitation, tolerance for adjuvant chemotherapy, and length of hospital stay. The development of an 'Enhanced Recovery After Surgery' (ERAS) protocol for lung surgery has further reduced hospital stay and the need for opioids for analgesia. Despite the optimal implementation of the ERAS protocol, there are still patients who need to stay in the hospital longer than the median. The aim of this research is to investigate the reasons for this.

Conditions

Minimally Invasive Surgical Procedures; VATS; RATS Surgery; Pulmonary Lobectomy; Pulmonary Segmentectomy; Air Leakage; Postoperative Complication; Pain Postoperative

Outcome Measures

Primary Outcomes (1)

• Length of hospital stay (days)

  The primary objective is to investigate the length of hospital stay of patients undergoing minimally invasive thoracoscopic anatomical lung resection with peri-operative care according to the Enhanced Recovery After Surgery (ERAS) protocol for lung surgery

  immediately after surgery until hospital discharge (1 week on average), up to 3 months

Secondary Outcomes (2)

• Reasons for delayed discharge (more than 2 days postoperatively) identified through daily questionnaires and review of medical records.

  immediately after surgery until hospital discharge (1 week on average), up to 3 months

• Number, frequency and severity of postoperative complications during hospital stay.

  immediately after surgery until hospital discharge (1 week on average), up to 3 months

Study Arms (1)

Patients undergoing a minimally invasive anatomical lung resection

Patients undergoing a minimally invasive anatomical lung resection, receiving perioperative care according to the ERAS protocol for Lung Surgery

Procedure: VATS/RATS anatomical lung resection

Interventions

VATS/RATS anatomical lung resection PROCEDURE

Perioperative care according to the ERAS protocol for lung surgery

Also known as: VATS lobectomy, RATS lobectomy, VATS segmentectomy, RATS segmentectomy

Patients undergoing a minimally invasive anatomical lung resection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients scheduled for thoracoscopic anatomical lung resection. An estimated 136 patients should be included after power calculation

You may qualify if:

• Patients referred for elective minimally invasive (uniportal or multiportal video- or robot-assisted) anatomical lung resection (lobectomy or segmentectomy)
• Informed consent obtained pre-operatively
• Age 18 years or older

You may not qualify if:

• Patients younger than 18 years old
• Traumatic event as indication for lung resection
• Non-anatomical lung resections
• Thoracotomy
• Patients already hospitalized for other pathologies, pre-existent and not related to the lung surgery
• Urgent/emergency procedures

Sponsors & Collaborators

• University Hospital, Ghent: lead
• AZ Sint-Lucas Brugge: collaborator

Study Sites (2)

AZ Sint-Jan Brugge-Oostende AV

Bruges, Belgium

RECRUITING

Ghent University Hospital

Ghent, Belgium

RECRUITING

MeSH Terms

Conditions

Postoperative Complications; Pain, Postoperative

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Liesbeth Desender, MD, PhD

CONTACT

3293326148; Liesbeth.Desender@uzgent.be

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical professor

Study Record Dates

• First Submitted: October 1, 2024
• First Posted: October 15, 2024
• Study Start: November 12, 2024
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: January 15, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

BE (2)