NCT06630767

Brief Summary

Laparoscopic common bile duct exploration (LCBDE) is a minimally invasive procedure to treat common bile duct stones (CBDS). Perioperative anxiety, hunger, thirst, fatigue, pain, nausea, and vomiting can influence a patient's recovery after surgery and prolong the in-hospital stay. Enhanced Recovery After Surgery (ERAS) is a modern concept that aims to improve perioperative patient care by implementing an evidence-based, patient-centered team approach. However, few reports focused on the safety and efficacy of the ERAS program in LCBDE. Therefore, this paper aims to compare the outcome of the ERAS program and conventional (C) care for patients undergoing LCBDE

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
228

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2021

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2024

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 27, 2024

Completed
11 days until next milestone

First Posted

Study publicly available on registry

October 8, 2024

Completed
Last Updated

October 15, 2024

Status Verified

October 1, 2024

Enrollment Period

3.5 years

First QC Date

September 27, 2024

Last Update Submit

October 8, 2024

Conditions

Keywords

enhanced recovery after surgerylaparoscopic common bile duct exploration

Outcome Measures

Primary Outcomes (1)

  • Lenghth of hospital stay

    The duration from the surgery to discharge

    1 - 30 days

Secondary Outcomes (1)

  • Postoperative complications

    1 - 30 days

Study Arms (2)

ERAS-LCBDE

EXPERIMENTAL

Patients subjected to enhanced recovery after surgery care for laparoscopic common bile duct exploration

Procedure: ERAS

C-LCBDE

ACTIVE COMPARATOR

Patients subjected to conventional care for laparoscopic common bile duct exploration

Procedure: Conventional

Interventions

ERASPROCEDURE

Enhanced recovery after surgery (ERAS) programs are a combination of evidenced-based perioperative care approaches that work synergistically to improve recovery after surgery. The core elements of ERAS protocols are preoperative advice, optimization of diet, systematic analgesic and anesthetic regimes, and early mobilization.

Also known as: Enhanced recovery after surgery
ERAS-LCBDE
ConventionalPROCEDURE

Conventional care for patients subjected for laparoscopic common bile duct exploration

C-LCBDE

Eligibility Criteria

Age20 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients diagnosed with CBDS
  • American Society of Anesthesiologists (ASA) scores of I - II
  • Age 20-70 years

You may not qualify if:

  • Severe cholangitis
  • Severe pancreatitis
  • Mirizzi syndrome
  • Perforated gallbladder
  • Biliary peritonitis
  • Intrahepatic stones
  • Hepatobiliary malignancy
  • Pregnancy
  • Conversion to open surgery
  • Previous upper abdominal surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

South Valley University

Luxor, 83523, Egypt

Location

South Valley University

Qina, 83523, Egypt

Location

Related Links

MeSH Terms

Conditions

Choledocholithiasis

Interventions

Enhanced Recovery After SurgeryCongresses as Topic

Condition Hierarchy (Ancestors)

Common Bile Duct DiseasesBile Duct DiseasesBiliary Tract DiseasesDigestive System DiseasesCholelithiasis

Intervention Hierarchy (Ancestors)

Perioperative CareSurgical Procedures, OperativeOrganizationsHealth Care Economics and Organizations

Study Officials

  • Marwa N Alansary, Lecturer

    South Valley University

    STUDY DIRECTOR
  • Mohammed A Omar, Professor

    South Valley University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Mohammed Ahmed Omar

Study Record Dates

First Submitted

September 27, 2024

First Posted

October 8, 2024

Study Start

January 1, 2021

Primary Completion

June 30, 2024

Study Completion

June 30, 2024

Last Updated

October 15, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

Locations