Core Stabilization Exercises in Patients with Knee Osteoarthritis

NCT06621784 | Active Not Recruiting

• 1 other identifier: 2023/377
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Exercise plays a key role in the treatment of knee osteoarthritis, but there is no clear evidence on which type of exercise is most effective. Recent studies highlight the benefits of core stabilization exercises for improving knee stability. This study aims to demonstrate the effects of adding core stabilization exercises to conventional exercise therapy for patients with knee osteoarthritis.

Conditions

Exercise Training; Osteoarthritis, Knee; Core Stability; Muscle Thickness of the Quadriceps Femoris; Balance

Outcome Measures

Primary Outcomes (1)

• Change in Knee Injury and Osteoarthritis Outcome Score total and subscale scores after a 6-week exercise program

  The Knee Injury and Osteoarthritis Outcome Score is scored on a scale from 0 to 100, where 0 represents extreme knee problems and 100 indicates no knee problems. Higher scores indicate a better outcome, reflecting less pain and better function.

  Baseline and 1 week after the 6-week exercise program

Secondary Outcomes (3)

• Change in single-leg stance test durations after a 6-week exercise program

  Baseline and 1 week after the 6-week exercise program

• Change in quadriceps femoris muscle thickness after a 6-week exercise program

  Baseline and 1 week after the 6-week exercise program

• Change in Visual Analog Scale at rest and during activity after a 6-week exercise program

  Baseline and 1 week after the 6-week exercise program

Study Arms (2)

Traditional exercise (control) group

ACTIVE COMPARATOR

The first group followed a standard home exercise program for three times per week for six weeks

Other: Classical exercise therapy

core exercise group

ACTIVE COMPARATOR

The second group followed a standard home exercise program and core stabilization exercises for three times per week for six weeks

Other: Core stabilization exercises; Other: Classical exercise therapy

Interventions

Core stabilization exercises OTHER

In most studies, exercises focused on the extremities have been researched. We believe that the positive effects of the core region on walking and postural stability will play a significant role in the treatment of knee osteoarthritis.

core exercise group

Classical exercise therapy OTHER

In the first group of our study, we prescribed exercises that have been proven effective in many studies, are frequently prescribed, and focus on joint range of motion and quadriceps strengthening

Traditional exercise (control) group; core exercise group

Eligibility Criteria

• Age: 50 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of bilateral stage II or III knee osteoarthritis according to the Kellgren and Lawrence grading system
• Aged between 50 and 65 years
• Having a complaint of knee pain for at least 6 months
• No systemic diseases that may hinder exercise (such as uncontrolled hypertension, cardiac arrhythmia, heart failure, neurological sequelae, joint deformities, malignancy, etc.)

You may not qualify if:

• Having received physical therapy in the last 6 months
• Having undergone knee injection in the last 6 months
• Having had knee surgery
• Morbid obesity
• Presence or history of malignancy
• Individuals with severe visual impairment
• Individuals with a history of neurological or vestibular diseases that could cause balance problems, or patients using medications that may affect balance
• Individuals with serious cardiac, respiratory, or uncontrolled metabolic diseases

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, Bahçelievler, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• İrem Setenay ÖZKAN

  Istanbul Physical Medicine Rehabilitation Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: September 26, 2024
• First Posted: October 1, 2024
• Study Start: June 23, 2023
• Primary Completion: June 23, 2024
• Study Completion: October 9, 2024
• Last Updated: October 4, 2024

Record last verified: 2024-09

Locations

TU (1)