NCT06619535

Brief Summary

The goal of this retrospective study is to explore the association between sepsis and morality among the elderly cancer patients. Data were extracted from the Surveillance, Epidemiology and End Results( SEER) database using SEER\*stat software. The study included patients aged 65 years or more who were diagnosed with cancer from 2000 to 2021. The extracted data included age, race, marital status, sex, stage, surgery, chemotherapy and radiotherapy. Multiple primary session was used to calculate the standardized Mortality ratio (SMR) as Observed/Expected with excess risk/10,000 and significance was achieved at 0.05.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,239,194

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2000

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2000

Completed
22 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2021

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

September 21, 2024

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 1, 2024

Completed
Last Updated

October 1, 2024

Status Verified

September 1, 2024

Enrollment Period

22 years

First QC Date

September 21, 2024

Last Update Submit

September 27, 2024

Conditions

SepsisCancer

Keywords

sepsisCancermortalitySMRSEER

Outcome Measures

Primary Outcomes (1)

  • SMR for sepsis as a cause of death among elderly cancer patients

    Patients were followed up from the time of diagnosis and the risk was assessed across different time intervals: 1 year, 5 years and +10 years after cancer diagnosis from 2000 to 2021

    from Jan, 2000 till Dec, 2021

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

elderly cancer patients

You may qualify if:

  • cancer patients
  • age 65 year or more

You may not qualify if:

  • \- Death certificate only and autopsy only cases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Suez Canal University

Ismailia, Egypt

Location

MeSH Terms

Conditions

SepsisNeoplasms

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Resident physician of gastroenterology

Study Record Dates

First Submitted

September 21, 2024

First Posted

October 1, 2024

Study Start

January 1, 2000

Primary Completion

December 30, 2021

Study Completion

December 30, 2021

Last Updated

October 1, 2024

Record last verified: 2024-09

Locations

EG(1)