Autogenous Dentin Derived Barrier Membrane Versus Collagen Membrane
DDBM dental
1 other identifier
interventional
20
1 country
2
Brief Summary
Autogenous Dentin Derived Barrier Membrane versus Collagen Membrane
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2022
Typical duration for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 10, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 10, 2024
CompletedFirst Submitted
Initial submission to the registry
September 7, 2024
CompletedFirst Posted
Study publicly available on registry
September 26, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 10, 2024
CompletedSeptember 26, 2024
September 1, 2024
2 years
September 7, 2024
September 24, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
All patients were evaluated radiographically immediately postoperative,and after 12 months
Radiographic Evaluation Cone Beam Computed Tomography scan was taken to measure Marginal Bone loss and Relative bone density
1 year
Study Arms (2)
Autogenous Dentin Derived Barrier Membrane
EXPERIMENTALAutogenous Dentin Derived Barrier Membrane + Xenogeneic bone graft material+ immediate implant
Collagen Membrane
EXPERIMENTALCollagen Membrane + Xenogeneic bone graft material + immediate implant
Interventions
tooth extraction , preparation of dentin membrane ,immediate implantation ,Xenogeneic bone graft material, application of dentin derived barrier membrane
like group one but with application of collagen membrane
Eligibility Criteria
You may qualify if:
- Patient's age ranges from 18-50 years.
- Adequate inter-arch relation and inter-occlusal space that could accommodate the implant abutment and the future restoration
- Non-restorable tooth that needs dental extraction \& guided bone regeneration for immediate implant.
- Presence of alveolar bone defect with vertical loss of buccal bone more than a third implant thread.
- Co-operative patients willing to complete the follow-up periods.
You may not qualify if:
- Any pathological condition at site of surgery.
- Patients with systemic diseases that contra-indicate the surgical procedure.
- Heavy smoking.
- Parafunctional habits such as bruxism and clenching.
- Pregnant patients. -
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Mansoura University, faculty of dentistry ,Department of Oral and Maxillofacial
Al Mansurah, Eygpt, 002, Egypt
Elhussein Farag
Al Mansurah, Eygpt, Egypt
Related Publications (1)
Mohamad EHFA, Awad S, Abbas MH, Elsheikh HA. Autogenous dentin-derived membrane as a biologic alternative to collagen membrane for guided bone regeneration in immediate implant placement in the posterior mandible: a randomized clinical trial. Odontology. 2025 Dec 10. doi: 10.1007/s10266-025-01271-6. Online ahead of print.
PMID: 41372516DERIVED
Study Officials
- STUDY CHAIR
Heba Elsheikh Assistant professor, Assistant professor
Mansoura University, faculty of dentistry ,Department of Oral and Maxillofacial
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 7, 2024
First Posted
September 26, 2024
Study Start
April 10, 2022
Primary Completion
April 10, 2024
Study Completion
October 10, 2024
Last Updated
September 26, 2024
Record last verified: 2024-09