Evaluation of the French Version of the PEERS Social Skills Training Program for Adolescents With Rare Neurodevelopmental Disorders

NCT06612333 | Completed

• 1 other identifier: HJ-23-PEERS-MRND
• Study Type: observational
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

Adolescents and young adults with rare neurodevelopmental disorders are at risk of developing psychiatric pathologies during the transition to adulthood. Loneliness and lack of social relationships can lead to anxiety and depression in adolescents and young adults with rare neurodevelopmental disorders. Anxiety and depression are major risk factors for the transition to psychiatric symptoms in adulthood. The improvement of social skills and the positive evolution of social relationships in adolescents and young adults with rare neurodevelopmental disorders can lead to a reduction in the risk factors for anxiety and depression. It therefore seems essential to evaluate the evolution of social skills in this population of young adults under the care of the social skills program, PEERS, in France to assess the overall benefit of the program, particularly in this population of young people with rare neurodevelopmental disorders.

Conditions

Neurodevelopmental Disorders; Rare Diseases

Outcome Measures

Primary Outcomes (7)

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases participating in the social skills program

  Quality of Play Questionnaire-Adolescent (QPQ-A) (QSQP in French)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Friendship Quality Scale (FQS)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Social Anxiety Scale for Adolescent (SAS-A)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Loneliness and Social Dissatisfaction Scale (L\&SD)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Test of Adolescent Social Skills Knowledge (TASSK)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Self-Assessment of Conversational Skills (AHC)

  2023 - 2025

• Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases

  Beck Youth Inventories (BYI)

  2023 - 2025

Study Arms (2)

Patient

Inclusion criteria: * Aged between 12 and 30 years, included at the start of the social skills program. * Patients with rare neurodevelopmental diseases * Patients benefiting from the social skills program * Appropriate level of verbal elaboration * Patient with a family member or a friend also participating in the social skills program Non-inclusion criteria : * Opposition of the patient or, if a minor, of his/her parents to participation in the study * Patient not psychiatrically stabilized: acute symptoms of anxiety, depression, psychotic disorders. * Severe intellectual disability

Family member or friend

Inclusion criteria: * be over 18 years * be a close relative or friend of a patient and share in his or her daily life * have taken or are taking the social skills program Non-inclusion criteria : \- Opposition to participation in the study

Eligibility Criteria

• Age: 12 Years - 30 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study will focus on data from 40 patients with rare neurodevelopmental disorders and their 40 relatives/friends.

You may qualify if:

• Aged between 12 and 30 years, included at the start of the social skills program.
• Patients with rare neurodevelopmental diseases
• Patients benefiting from the social skills program
• Appropriate level of verbal elaboration
• Patient with a family member or a friend also participating in the social skills program
• Opposition of the patient or, if a minor, of his/her parents to participation in the study
• Patient not psychiatrically stabilized: acute symptoms of anxiety, depression, psychotic disorders.
• Severe intellectual disability

Sponsors & Collaborators

• Imagine Institute: lead

Study Sites (1)

Necker - Enfants Malades Hospital

Paris, Île-de-France Region, 75015, France

Location

MeSH Terms

Conditions

Neurodevelopmental Disorders; Rare Diseases

Condition Hierarchy (Ancestors)

Mental Disorders; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 26, 2024
• First Posted: September 25, 2024
• Study Start: May 1, 2024
• Primary Completion: October 17, 2025
• Study Completion: October 17, 2025
• Last Updated: November 19, 2025

Record last verified: 2025-11

Locations

FR (1)