NCT06605924

Brief Summary

This study tests the effects of three oral nicotine marketing features on product perceptions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,133

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 18, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 20, 2024

Completed
8 months until next milestone

Study Start

First participant enrolled

May 12, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 18, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 18, 2025

Completed
Last Updated

January 29, 2026

Status Verified

January 1, 2026

Enrollment Period

6 months

First QC Date

September 18, 2024

Last Update Submit

January 27, 2026

Conditions

Outcome Measures

Primary Outcomes (6)

  • Absolute perceived harm

    How harmful participant perceives the product to be. Participants will answer a survey item, How harmful do you think this product is to your health; with response options ranging from 0-Not at all harmful to 4-Extremely harmful.

    Immediately after viewing ad

  • Relative perceived harm

    How harmful participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item, Compared to the following products \[cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco; alcohol; cannabis\], how harmful do you think the advertised product is? with response options ranging from 0-a lot less harmful to 4-a lot more harmful.

    Immediately after viewing ad

  • Absolute perceived addictiveness

    How addictive participant perceives the product to be. Participants will answer a survey item, How addictive do you think this product is; with response options ranging from 0-not at all addictive to 4-extremely addictive.

    Immediately after viewing ad

  • Relative perceived addictiveness

    How addictive participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item; Compared to the following products \[cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco products; alcohol; cannabis\], how addictive do you think the advertised product is; with response options ranging from 0-a lot less addictive to 4-a lot more addictive.

    Immediately after viewing ad

  • Product appeal

    How appealing participant perceives the product to be. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am curious about the product in the ad;, with response options from 0-strongly disagree to 4-strongly agree.

    Immediately after viewing ad

  • Use intention

    Perceived likelihood of using the product. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am interested in using the product in the ad, with response options from 0-strongly disagree to 4-strongly agree.

    Immediately after viewing ad

Secondary Outcomes (2)

  • Perceived ability to satisfy nicotine cravings

    Immediately after viewing ad

  • Perceived ability to help one quit smoking

    Immediately after viewing ad

Study Arms (4)

Tobacco-free

EXPERIMENTAL

Viewing a static advertisement

Other: Tobacco-free

Discrete

EXPERIMENTAL

Viewing a static advertisement

Other: Discrete

Convenient

EXPERIMENTAL

Viewing a static advertisement

Other: Convenient

Control

NO INTERVENTION

Viewing a static advertisement - baseline language only

Interventions

Ad contains baseline language + language that product is tobacco-free

Tobacco-free

Ad contains baseline language + language that product is discrete

Discrete

Ad contains baseline language + language that product is convenient

Convenient

Eligibility Criteria

Age13 Years - 120 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Live in the US
  • For youth age \<21: Never used any nicotine pouch
  • For adults: Smoked greater than or equal to 100 cigarettes in during lifetime
  • For adults: Currently smoke some or all days
  • For adults: No regular use of oral nicotine pouches
  • For adults: No past 30-day pouch use

You may not qualify if:

  • Do not live in the US
  • For youth age \<21: Ever used nicotine pouches
  • For youth age \<21: Greater than or equal to 100 lifetime uses of any other nicotine or tobacco product
  • For adults: Smoked \<100 cigarettes in life
  • For adults: Does not currently smoke some or all days
  • For adults: Regular use of oral nicotine pouches
  • For adults: Past 30-day pouch use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

2213 McElderry St.

Baltimore, Maryland, 21205, United States

Location

MeSH Terms

Conditions

Tobacco Use

Interventions

Divorce

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Marital StatusFamily CharacteristicsDemographyPopulation CharacteristicsSocioeconomic Factors

Study Officials

  • Meghan Moran, PhD

    Johns Hopkins University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Model Details: Participants will view ads in each of four conditions manipulating presence of different marketing features.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 18, 2024

First Posted

September 20, 2024

Study Start

May 12, 2025

Primary Completion

November 18, 2025

Study Completion

November 18, 2025

Last Updated

January 29, 2026

Record last verified: 2026-01

Locations