Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking

NCT06546618 | Completed Results DMC

• 2 other identifiers: 24-0841R01CA240732
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this research is to determine how removal of little cigar and cigarillo (LCC) flavor descriptors on packaging impacts attention and affective responses to LCC warnings. A study will be conducted using eye tracking, electrodermal activity (galvanic skin response), and survey measures of affect to measure participant responses to LCC packages varied by warning type (pictorial vs. text only) and flavor contents ('Sweet' flavor descriptor vs. no flavor descriptor).

Conditions

Tobacco Use

Keywords

Text-only warning messages; LCC packages with flavor descriptors; pictorial warnings messages; LCC packages without flavor descriptors

Outcome Measures

Primary Outcomes (2)

• Attention to Warning Areas of Interest

  Mean attention to warning areas of interest in seconds will be measured by dwell time to pre-defined areas of interest on the LCC packages. The mean amount of time in seconds that participants spend looking at the flavor area of interest for the 3 packages in each condition will be determined.

  During one time study appointment

• Attention to Flavor Areas of Interest

  Mean attention to flavor areas of interest in seconds will be measured by dwell time to pre-defined areas of interest on the LCC packages. The mean amount of time in seconds that participants spend looking at the flavor area of interest for the 3 packages in each condition will be determined.

  During one time study appointment

Secondary Outcomes (2)

• Positive Affect

  During one time study appointment

• Negative Affect

  During one time study appointment

Study Arms (1)

All Participants

OTHER

All participants saw LCC pack stimuli images presented in random order, 4 package conditions were repeated with 3 warnings applied to each (12 stimuli total).

Behavioral: LCC pack stimuli images

Interventions

LCC pack stimuli images BEHAVIORAL

All participants saw LCC pack stimuli images presented in random order, 4 package conditions were repeated with 3 warnings applied to each (12 stimuli total).

All Participants

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Over 21 years old
• Pass quality/bot screening (will answer honestly, captcha, simple math question)
• Speak English
• Current every day or some day users of LCC products
• Able to come to an appointment in NC triangle area
• Do not have any eye conditions that prevent them from being eye tracked (e.g., glaucoma, lazy eye, bifocals)

You may not qualify if:

• Under 21 years old
• Do not speak English
• Unable to pass quality/bot screening
• Unable to come to an appointment
• Eye conditions that prevent eye tracking (e.g., glaucoma, lazy eye, bifocals)

Sponsors & Collaborators

• UNC Lineberger Comprehensive Cancer Center: lead
• National Cancer Institute (NCI): collaborator
• Food and Drug Administration (FDA): collaborator

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

Location

Related Links

• University of North Carolina Lineberger Comprehensive Cancer Center Clinical Trials

MeSH Terms

Conditions

Tobacco Use

Condition Hierarchy (Ancestors)

Behavior

Results Point of Contact

• Title: Adam O Goldstein
• Organization: UNC Lineberger Comprehensive Cancer Center

AOG@med.unc.edu

919-270-6491

Study Officials

• Adam O Goldstein

  UNC Lineberger Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: All participants saw LCC pack stimuli images presented in random order, 4 package conditions were repeated with 3 warnings applied to each (12 stimuli total).

Study Record Dates

• First Submitted: August 6, 2024
• First Posted: August 9, 2024
• Study Start: August 14, 2024
• Primary Completion: March 5, 2025
• Study Completion: March 5, 2025
• Last Updated: July 2, 2026
• Results First Posted: July 2, 2026

Record last verified: 2026-06

Locations

US (1)