Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking

NCT06546618 | Completed DMC

• 2 other identifiers: 24-0841R01CA240732
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this research is to determine how removal of little cigar and cigarillo (LCC) flavor descriptors on packaging impacts attention and affective responses to LCC warnings. A study will be conducted using eye tracking, electrodermal activity (galvanic skin response), and survey measures of affect to measure participant responses to LCC packages varied by warning type (pictorial vs. text only) and flavor contents ('Sweet' flavor descriptor vs. no flavor descriptor).

Conditions

Tobacco Use

Keywords

Text-only warning messages; LCC packages with flavor descriptors; pictorial warnings messages; LCC packages without flavor descriptors

Outcome Measures

Primary Outcomes (2)

• Attention to warning areas of interest

  Attention to warning areas of interest will be measured by dwell time to pre-defined areas of interest on the little cigars or cigarillos (LCCs) package. The total amount of time in iseconds that participants spend looking at warnings will be determined.

  Baseline

• Attention to flavor area of interest

  Attention to flavor area of interest will be measured by dwell time to pre-defined areas of interest on the little cigars or cigarillos (LCCs) package. The total amount of time inseconds that people spend looking at the area where the flavor of the LCC is shown will be determined.

  Baseline

Secondary Outcomes (2)

• Electrodermal activity

  Baseline

• Affective response to warnings

  Baseline

Study Arms (4)

LCC Package with pictorial warning and no flavor

EXPERIMENTAL

Participants will see a mock LCC package with pictorial warnings and no flavor descriptor.

Behavioral: pictorial warning and no flavor

LCC Package with pictorial warning and 'sweet' flavor

EXPERIMENTAL

Participants will see a mock LCC package with pictorial warnings and a 'sweet' flavor descriptor.

Behavioral: pictorial warning and 'sweet' flavor

LCC Package with text-only warning and no flavor

EXPERIMENTAL

Participants will see a mock LCC package with text-only warnings and no flavor descriptor.

Behavioral: text-only warning and no flavor

LCC Package with text-only warning and 'sweet' flavor

EXPERIMENTAL

Participants will see a mock LCC package with text-only warnings and a 'sweet' flavor descriptor

Behavioral: text-only warning and 'sweet' flavor

Interventions

pictorial warning and no flavor BEHAVIORAL

LCC Package with pictorial warning and no flavor

LCC Package with pictorial warning and no flavor

pictorial warning and 'sweet' flavor BEHAVIORAL

LCC Package with pictorial warning and 'sweet' flavor

LCC Package with pictorial warning and 'sweet' flavor

text-only warning and no flavor BEHAVIORAL

LCC Package with text-only warning and no flavor

LCC Package with text-only warning and no flavor

text-only warning and 'sweet' flavor BEHAVIORAL

LCC Package with text-only warning and 'sweet' flavor

LCC Package with text-only warning and 'sweet' flavor

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Over 21 years old
• Pass quality/bot screening (will answer honestly, captcha, simple math question)
• Speak English
• Current every day or some day users of LCC products
• Able to come to an appointment in NC triangle area
• Do not have any eye conditions that prevent them from being eye tracked (e.g., glaucoma, lazy eye, bifocals)

You may not qualify if:

• Under 21 years old
• Do not speak English
• Unable to pass quality/bot screening
• Unable to come to an appointment
• Eye conditions that prevent eye tracking (e.g., glaucoma, lazy eye, bifocals)

Sponsors & Collaborators

• UNC Lineberger Comprehensive Cancer Center: lead
• National Cancer Institute (NCI): collaborator
• Food and Drug Administration (FDA): collaborator

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

Location

Related Links

• University of North Carolina Lineberger Comprehensive Cancer Center Clinical Trials

MeSH Terms

Conditions

Tobacco Use

Interventions

Candy

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Adam O Goldstein

  UNC Lineberger Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 6, 2024
• First Posted: August 9, 2024
• Study Start: August 14, 2024
• Primary Completion: March 5, 2025
• Study Completion: March 5, 2025
• Last Updated: September 16, 2025

Record last verified: 2024-09

Locations

US (1)