The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia

NCT06601894 | Not Yet Recruiting DMC FDA Device

• 1 other identifier: IRB Log No.: 29-EP-2024
• Study Type: observational
• Target: 650
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.

Conditions

Sickle Cell Anaemia; SCD

Outcome Measures

Primary Outcomes (1)

• Collecting platelet data for sickle cell anemia patients

  Collecting platelet data for sickle cell anemia patients in males and female and children based on different ages, then analyzing them and studying their relationship

  From January 2023 to December 2023

Study Arms (3)

Males

The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia.

Diagnostic Test: Platelets count

Children

The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia.

Diagnostic Test: Platelets count

Females

The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia.

Diagnostic Test: Platelets count

Interventions

Platelets count DIAGNOSTIC_TEST

the study include will take medical investigation data for all sickle cell patients.

Children; Females; Males

Eligibility Criteria

• Age: 1 Year+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will include a cohort of people with SCD who are registered at the Hereditary Blood center al-ahssa.

Sponsors & Collaborators

• Majmaah University: lead

Study Sites (1)

Khalid Ali Majrashi

Dammam, Saudi Arabia

Location

Related Publications (3)

• Wun T, Paglieroni T, Rangaswami A, Franklin PH, Welborn J, Cheung A, Tablin F. Platelet activation in patients with sickle cell disease. Br J Haematol. 1998 Mar;100(4):741-9. doi: 10.1046/j.1365-2141.1998.00627.x.

  PMID: 9531343 RESULT

• Shome DK, Jaradat A, Mahozi AI, Sinan AS, Ebrahim A, Alrahim M, Ebraheem MS, Mansoor EJ, Majed KS, Azeez Pasha SA. The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care. Indian J Crit Care Med. 2018 Aug;22(8):585-590. doi: 10.4103/ijccm.IJCCM_49_18.

  PMID: 30186009 RESULT

• Yee MEM, Batsuli G, Chonat S, Park S. Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease. Clin Case Rep. 2020 Nov 20;9(1):457-460. doi: 10.1002/ccr3.3556. eCollection 2021 Jan.

  PMID: 33489197 RESULT

MeSH Terms

Conditions

Anemia, Sickle Cell

Interventions

Platelet Count

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, Congenital; Anemia, Hemolytic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Hemoglobinopathies; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Blood Cell Count; Cell Count; Cytological Techniques; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Hematologic Tests; Platelet Function Tests; Investigative Techniques; Cell Physiological Phenomena; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Study Officials

• Khalid A Majrashi

  Majmaah University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Khalid A Majrashi

CONTACT

0533489978; khalid77555@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Student

Study Record Dates

• First Submitted: September 16, 2024
• First Posted: September 19, 2024
• Study Start: December 1, 2024
• Primary Completion: December 31, 2024
• Study Completion: March 30, 2025
• Last Updated: October 4, 2024

Record last verified: 2024-10

Locations

SA (1)