Prolonged Mechanical Ventilation in Neurosurgical Patients:

NCT06591624 | Completed DMC

• 2 other identifiers: ANE-2565-09317Chiang Mai University
• Study Type: observational
• Target: 340
• Locations: 1 country
• Sites: 1

Brief Summary

The study was carried out at the neurosurgical operating theater and neurosurgical intensive care unit, Maharaj Nakorn Chiang Mai University-Hospital. The study design was a retrospective Cohort study, recruited elective adult neurosurgical patients during December 1, 2021 to December 31, 2022. The patients were excluded if they had pre-operative definite airway control. The primary outcome was extubation success in the operating theater. Prolonged mechanical ventilation (PMV) means the patients who could not undergo the weaning protocol and extubation in 48 hours of surgery. The secondary outcome was the features associated with the prolonged mechanical ventilation.

Conditions

Neurosurgical Procedures; Neurosurgical Patients; Prolonged Mechanical Ventilation

Keywords

ventilator dependent; neurosurgical patient; prolonged mechanical ventilation

Outcome Measures

Primary Outcomes (1)

• to be able to extubate after neurosurgery

  successful extubation

  within 24 hours after surgery

Study Arms (2)

elective adult neurosurgical patients succesfully extubation after neurosurgery

succesfully extubation after neurosurgery

Other: remain intubation after surgery

elective adult neurosurgical patients prolonged mechanical ventilation

prolonged mechanical ventilation

Other: Prolonged Mechanical Ventilation

Interventions

Prolonged Mechanical Ventilation OTHER

The neurosurgical patients who could extubated within 24 h after surgery

elective adult neurosurgical patients prolonged mechanical ventilation

remain intubation after surgery OTHER

could not extubated after surgery and prolong mechanical ventilation for 48 hours

elective adult neurosurgical patients succesfully extubation after neurosurgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study was carried out at the neurosurgical operating theater and neurosurgical intensive care unit, Maharaj Nakorn Chiang Mai University-Hospital. The study design was a retrospective Cohort study, recruited elective adult neurosurgical patients during December 1, 2021 to December 31, 2022. The patients were excluded if they had pre-operative definite airway control such as intubation or tracheostomy.

You may qualify if:

• adult neurosurgical patients
• undergo elective surgery

You may not qualify if:

• already intubation before neurosurgical procedures
• tracheostomy

Sponsors & Collaborators

• Chiang Mai University: lead

Study Sites (1)

Chiang Mai University

Chiang Mai, Chiang Mai, 50200, Thailand

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: September 8, 2024
• First Posted: September 19, 2024
• Study Start: January 10, 2021
• Primary Completion: December 31, 2023
• Study Completion: December 31, 2023
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)