Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

NCT05634135 | Recruiting

• 1 other identifier: 202112183RIND
• Study Type: observational
• Target: 103
• Locations: 1 country
• Sites: 1

Brief Summary

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

Conditions

Prolonged Mechanical Ventilation

Keywords

Ventilation; mechanical ventilation; weaning; oxygen uptake

Outcome Measures

Primary Outcomes (1)

• Liberation from mechanical ventilation at discharge from the weaning unit

  At least five consecutive days of free from mechanical ventilation ventilation

  Five days

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Chronic critically ill patients receiving prolonged mechanical ventilation

You may qualify if:

• Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training
• Patients who have undergone tracheostomy and still have a tracheotomy tube
• Are at least 20 years old
• Stable respiratory condition with inspired oxygen fraction not exceeding 50%

You may not qualify if:

• Hemodynamic instability or continuous use of vasopressors
• Pregnancy

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

RECRUITING

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Jih-Shuin Jerng, MD, PhD

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jih-Shuin Jerng, MD, PhD

CONTACT

+886-2-23123456; jsjerng@ntu.edu.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 21, 2022
• First Posted: December 1, 2022
• Study Start: July 31, 2022
• Primary Completion: February 17, 2025
• Study Completion: February 17, 2025
• Last Updated: December 30, 2024

Record last verified: 2024-09

Locations

TW (1)