The Effect of Anxiety on Pain-pressure Threshold in a Healthy Population

NCT06586086 | Suspended

• 1 other identifier: 082419
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study recruit individuals who are 18 years of age AND Do NOT have a history of diagnosed anxiety disorders AND Do NOT currently have any area of pain lasting 3 months or longer. The study will measure discomfort with a controlled application of pressure to different muscles and compare these measures with the individual's score on a standardized assessment of anxiety.

Conditions

Healthy

Keywords

Healthy

Outcome Measures

Primary Outcomes (1)

• Pain-Pressure Threshold

  Quantitative measurement of the amount of pressure applied at the point when the subject described the pressure as slight discomfort

  A single collection session of data for each participant, lasting approximately 30 minutes, performed after completion of the STAI-5. Total Data collection window is 4 months.

Secondary Outcomes (1)

• State-Trait Anxiety questionnaire (STAI)-5 question form

  A single collection session of data for each participant, lasting approximately 5 minutes. Total Data collection window is 4 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy volunteers.

You may qualify if:

• Adults 18 years of age or older
• Able to read and complete the STAI-5 questionnaire as written in English

You may not qualify if:

• Pain lasting three months or longer, located anywhere in the body
• Severe health problem (such as cancer, cardiac, neurologic or psychiatric/anxiety disorders),
• Current pregnancy and/or gave birth in the last year.
• Subjects currently taking medication which may impact sensory processing, such as antidepressants, opioids, neuroleptics, anticonvulsive drugs or steroids.
• Subjects diagnosed with fibromyalgia or other conditions known to reduce muscular pain-pressure thresholds, such as Lyme disease, polymyalgia, Lupus and Rheumatoid Arthritis.

Sponsors & Collaborators

• Philadelphia College of Osteopathic Medicine: lead

Study Sites (1)

Philadelphia College of Osteopathic Medicine-Georgia Campus

Suwanee, Georgia, 30024, United States

Location

Study Officials

• Dr. Lowe

  PCOM GA

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 16, 2024
• First Posted: September 19, 2024
• Study Start: October 29, 2024
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: July 31, 2025

Record last verified: 2025-07

Locations

US (1)