NCT06573203

Brief Summary

In this study, hospitalized neonates were taken as the focus of the study. The non-contact heart rate and respiratory rate monitoring system was used to measure heart rate, respiratory rate, sleep parameters, ECG monitor, neonatal sleep-wake scale, amplitude-integrated electroencephalography. aEEG), in order to provide a theoretical basis for standardizing the operation of medical staff and formulating sleep protection strategies in the future, so as to promote the sleep quality of hospitalized neonates and improve the prognosis of neonates.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
8mo left

Started Aug 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress73%
Aug 2024Dec 2026

First Submitted

Initial submission to the registry

August 20, 2024

Completed
1 day until next milestone

Study Start

First participant enrolled

August 21, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 27, 2024

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2026

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

March 5, 2025

Status Verified

August 1, 2024

Enrollment Period

2 years

First QC Date

August 20, 2024

Last Update Submit

March 3, 2025

Conditions

Keywords

Sleep monitoringVital signs were monitoredStudy of correlation

Outcome Measures

Primary Outcomes (4)

  • Sleep-wake state

    Sleep-wake state scores derived from a contact-free heart rate and respiratory rate monitoring system and NSWST measurements.

    10minutes after the meal, 5minutes each time, two times in total

  • Number of sleep cycles

    The number of sleep cycles obtained was monitored simultaneously by a non-contact heart rate and respiratory rate monitoring system and aEEG.

    The hospital stay lasted 6 hours

  • Proportion of quiet sleep

    non-contact heart rate and respiratory rate monitoring system and aEEG were used to simultaneously measure the quiet sleep time for 6 hours, and then the proportion of quiet sleep was calculated.

    The hospital stay lasted 6 hours

  • Proportion of active sleep

    non-contact heart rate and respiratory rate monitoring system and aEEG were used to simultaneously measure the active sleep time for 6 hours, and then the proportion of active sleep was calculated.

    The hospital stay lasted 6 hours

Secondary Outcomes (2)

  • Heart rate

    The hospital stay lasted 6 hours

  • Respiratory rate

    The hospital stay lasted 6 hours

Study Arms (4)

Non-contact heart rate and respiratory rate monitoring system

EXPERIMENTAL

After admission, the non-contact mattress is placed under a normal mattress, and heart rate, respiratory rate, and sleep-related parameters can be collected through induction.

Device: Mindray ECG monitorDevice: aEEGOther: Neonatal Sleep-Wake Assessment Tool (NSWAT) included four dimensions: eye movement, respiratory rate, facial expression and muscle activity.

Electrocardiogram monitor

ACTIVE COMPARATOR

Measuring vital signs

Device: Non-contact heart rate and respiratory rate monitoring system

Amplitude-integrated EEG

ACTIVE COMPARATOR

Sleep parameters were continuously measured by aEEG for 6 hours after admission.

Device: Non-contact heart rate and respiratory rate monitoring system

Neonatal Sleep-Wake Assessment Tool

ACTIVE COMPARATOR

It is suitable for all newborns to observe and evaluate the sleep phase, wake period and regularity, and guide the choice of care time. The scale includes four dimensions: eye movement, breathing rate, facial expression and muscle activity. The score range of each dimension is 0 \~ 2 points, and the score range is 0 \~ 8 points.

Device: Non-contact heart rate and respiratory rate monitoring system

Interventions

Each neonate enrolled underwent four sleep and vital signs monitoring procedures after admission.

Also known as: model YBB-B1
Amplitude-integrated EEGElectrocardiogram monitorNeonatal Sleep-Wake Assessment Tool

Heart rate and respiratory rate of each enrolled child were monitored after admission.

Also known as: model cPM 10C
Non-contact heart rate and respiratory rate monitoring system
aEEGDEVICE

Each enrolled child underwent a 6-hour sleep-wake cycle, quiet sleep, and active sleep monitoring after admission.

Also known as: model Nicolet EEG V32
Non-contact heart rate and respiratory rate monitoring system

The study nurses observed and scored the children's sleep-wake status 10 minutes after two meals during the mattress test period, each time for 5 minutes.

Non-contact heart rate and respiratory rate monitoring system

Eligibility Criteria

Age1 Day - 1 Month
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Newborns admitted to our hospital for the first time, with gestational age ≥28w;
  • Expected hospital stay ≥5 days.

You may not qualify if:

  • Apgar score ≤3 at 1 or 5 min after birth;
  • Severe congenital malformation; Severe hypoxic-ischemic encephalopathy, intraventricular hemorrhage of grade III and above; There were serious heart and lung diseases.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Children's Hospital Affiliated to the Medical College of Zhejiang University

Hangzhou, Zhejiang, 310000, China

Location

MeSH Terms

Interventions

Respiratory Rate

Intervention Hierarchy (Ancestors)

Vital SignsPhysical ExaminationDiagnostic Techniques and ProceduresDiagnosisRespirationRespiratory Physiological PhenomenaCirculatory and Respiratory Physiological Phenomena

Study Officials

  • Hongzhen Xu

    The Children's Hospital Affiliated to the Medical College of Zhejiang University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Honorary Director of Nursing Department

Study Record Dates

First Submitted

August 20, 2024

First Posted

August 27, 2024

Study Start

August 21, 2024

Primary Completion (Estimated)

August 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

March 5, 2025

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will not share

Locations