NCT06514833

Brief Summary

To examine the effects of napping in pregnant women with sleep disturbances on offspring neurodevelopment, the researchers will recruit 80 pregnant women with sleep disturbances. These women will receive lifestyle recommendations to nap regularly and will choose whether or not to nap. The participants will wear wrist-worn accelerometers to record their 24-hour sleep patterns for seven consecutive days during the early, middle, and late stages of pregnancy. The neurodevelopment of their offspring will be assessed at 6 months, 12 months, 18 months, and 2 years of age.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
28mo left

Started Aug 2024

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress44%
Aug 2024Aug 2028

First Submitted

Initial submission to the registry

July 17, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 23, 2024

Completed
27 days until next milestone

Study Start

First participant enrolled

August 19, 2024

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 18, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 18, 2028

Last Updated

July 23, 2024

Status Verified

July 1, 2024

Enrollment Period

4 years

First QC Date

July 17, 2024

Last Update Submit

July 22, 2024

Conditions

Keywords

Sleep disturbanceNeurodevelopment

Outcome Measures

Primary Outcomes (1)

  • Bayley Scales of Infant and Toddler Development score

    The Bayley Scales of Infant and Toddler Development (Bayley-III) evaluates five key developmental domains: 1. Cognitive Development. 2. Language Development. 3. Motor Development. 4. Social-Emotional Development. 5. Adaptive Behavior.

    Children at 24 months

Secondary Outcomes (2)

  • Ages and Stages Questionnaires (ASQ) score

    Children at 12 months

  • Ages and Stages Questionnaires (ASQ) score

    Children at 6 months

Study Arms (2)

Nap

EXPERIMENTAL

The experimental group will receive lifestyle recommendations to nap regularly

Behavioral: lifestyle recommendations to nap regularly

No nap

OTHER

The control group would not receive lifestyle recommendations to nap regularly

Other: No recommendations to nap regularly

Interventions

Participants will receive lifestyle recommendations to nap regularly for 15-30 minutes between 12:00 and 15:00

Nap

No lifestyle recommendations to nap regularly

No nap

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Pregnant women with a PSQI score greater than 5 at enrollment.
  • Not a habitual napper in the past 3 months (defined as napping 5 or more days per week on average for the past month).

You may not qualify if:

  • Women with severe respiratory or cardiovascular diseases, liver or kidney dysfunction, or malignant tumors.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Xinhua Hospital Affiliated to Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, 200092, China

Location

MeSH Terms

Conditions

Parasomnias

Condition Hierarchy (Ancestors)

Sleep Wake DisordersNervous System DiseasesMental Disorders

Study Officials

  • Yun Huang, Ph.D.

    Xinhua Hospital Affiliated to Shanghai Jiao Tong University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Assessors responsible for conducting the neurodevelopment tests are blinded to the group allocation.
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 17, 2024

First Posted

July 23, 2024

Study Start

August 19, 2024

Primary Completion (Estimated)

August 18, 2028

Study Completion (Estimated)

August 18, 2028

Last Updated

July 23, 2024

Record last verified: 2024-07

Locations