Adaptation of Community Reinforcement Approach for the Treatment of Drug Addiction

NCT06559631 | Completed DMC

• 1 other identifier: Adaptation of CRA
• Study Type: interventional
• Target: 59
• Locations: 1 country
• Sites: 2

Brief Summary

Central idea of the study is to adapt a treatment program for drug addiction treatment indigenously and relapse prevention, and to establish its efficacy. This study helps the society to have an evidence-based approach with proven efficacy to deal with drugs related issues in Pakistan along with minimizing the rate of relapse which is the major issue with current disease model for treatment of addiction in different rehabs within the country. Present study's aim is to adapt culturally and islamically a robust treatment protocol: Reinforcement Approach (CRA) through randomized control trial to determine its efficacy in the field of drug addiction rehabilitation. Moreover, CRA is also be used with comorbid psychological illnesses. Because, in the treatment facilities disease model is currently prevailing which lacks empirical evidence, and they do not have proven efficacy.

Conditions

Substance Use Disorders; Comorbidities and Coexisting Conditions

Keywords

Substance Use Disorders; Treatment Model; Comorbid Mental Disorders; Residential Treatment

Outcome Measures

Primary Outcomes (1)

• Recovery

  Staying in abstinence from the drug of abuse. Recovery will be measured through Addiction Recovery Questionnaire (ARQ), this is a 4 point rating scale which measures normal living, abstinence and positive expectancy as recovery's subscales.

  First assessment will be conducted at the time of admission which will be completed till 21 days after admission. Second assessment after 120 days at the time of discharge. Third outcome measure during the follow up at the sixth month after discharge.

Secondary Outcomes (1)

• Comorbidities

  First assessment will be conducted at the time of admission which will be completed till 21 days after admission. Second assessment after 120 days at the time of discharge. Third outcome measure during the follow up at the sixth month after discharge.

Study Arms (2)

Treatment Group

EXPERIMENTAL

Experimental group will receive the indigenously adapted Community Reinforcement Approach based psychotherapeutic sessions after the completion of drugs related detoxification (after 21 days since hospitalization) for 90-120 days in residential treatment.

Behavioral: Indigenously Adapted CRA

Control Group: Treatment as usual

NO INTERVENTION

This group will receive treatment as usual which includes detoxification of drugs, general counselling for drug addiction prevention, 12 steps program and life skills training. Duration of residential treatment is between 90-120 days.

Interventions

Indigenously Adapted CRA BEHAVIORAL

Treatment group will receive psychotherapy based on CRA which is an evidence based approach. This adapted version of CRA also consists emotional management, behavioral interventions, drug addiction treatment and islamically integrated psychotherapy for drug addiction and comorbid mental disorders.

Treatment Group

Eligibility Criteria

• Age: 16 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient admitted for treatment of drug addiction with or without comorbid psychological disorders.

You may not qualify if:

• Patient with no history of drug abuse.

Sponsors & Collaborators

• Muhammad Saghir: lead

Study Sites (2)

Hayat Rehab Clinic (HRC)

Islamabad, 46500, Pakistan

Location

Islamabad Rehab Clinic (IRC)

Islamabad, 46500, Pakistan

Location

Related Links

• this is the link of a cite facility, Islamabad Rehab Clinic
• this is the link of a cite facility, Hayat Rehab Clinic

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Study Officials

• Dr. Mazhar Iqbal Bhatti

  International Islamic University, Islamabad

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: single-blind randomized controlled trial (RCT)
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Director of clinical affaires, Clinical Psychologist, Principal Investigator, at Islamabad Rehab Clinic.

Model Details: Research design of the study shall consists two-arms, single-blind randomized controlled trial (RCT). While Randomized Control Trial (RCT) shall consists of two groups: Active Treatment (AT) group and Control group

Study Record Dates

• First Submitted: January 31, 2024
• First Posted: August 19, 2024
• Study Start: February 4, 2022
• Primary Completion: July 25, 2023
• Study Completion: July 25, 2023
• Last Updated: August 19, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF, CSR

Locations

PA (2)