Home Treatment for Individuals Suffering From Severe Addictive Disorders

NCT05563363 | Recruiting

• 1 other identifier: not yet available
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Home Treatment (HT) has been successfully implemented in adult psychiatry in several countries including Switzerland. Patients with addiction problems were generally excluded even if the latter was not the main diagnosis. On the other hand, community treatments have successfully been established for these individuals. The investigators have recently offered HT to persons with severe addictive disorders which was well accepted. The investigators intend to conduct a pilot study to prepare a large-scale study if successful. The investigators intend to compare HT to treatment as usual (regular inpatient treatment) on a specialized ward with respect to readmission rates during 6 months after discharge. The data show that 70.8% of all readmissions occur during the first 6 months. Therefore, a period of 6 months is considered an adequate time interval to sufficiently answer this pilot study's question.

Conditions

Substance Use Disorders

Outcome Measures

Primary Outcomes (1)

• readmission rates

  Number of readmissions to hospital during the 6 months following discharge

  6 month post-discharge

Secondary Outcomes (5)

• time to readmission

  6 months

• length of hospitalization

  6 months

• number of emergency room visits

  6 months

• clinical outcome

  6 months

• patient satisfaction

  6 months

Study Arms (2)

Home treatment

EXPERIMENTAL

Home visits by care staff at the same frequency as in hospital

Other: Hospital-like treatment in patients' home

Standard inpatient treatment

ACTIVE COMPARATOR

Inpatient treatment on hospital ward

Other: standard inpatient treatment

Interventions

Hospital-like treatment in patients' home OTHER

Hospital-like treatment in patients' home. Caregivers, medical doctors and social workers will make several visits per day to the patients' home. 24/7 contact is available.

Home treatment

standard inpatient treatment OTHER

Inpatient treatment on addiction ward

Standard inpatient treatment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Substance use disorder
• age 18 or above
• sufficient french language skills
• competent subjects
• consent to randomization progress

You may not qualify if:

• organic brain disease or developmental disorder
• non voluntary admission
• severe somatic comorbidity
• History of complicated substance withdrawal
• acute suicidal ideation
• aggressive behavior
• acute psychiatric disease such as mania or psychosis
• distance to center (must be reachable within 60 minutes)

Sponsors & Collaborators

• Louise Penzenstadler: lead

Study Sites (1)

Geneva University Hospital

Geneva, Switzerland

RECRUITING

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Central Study Contacts

Louise Penzenstadler, MD

CONTACT

+41223725750; Louise.E.Penzenstadler@hcuge.ch

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dr

Model Details: Pilot study, randomized, open, non-blinded

Study Record Dates

• First Submitted: September 23, 2022
• First Posted: October 3, 2022
• Study Start: December 1, 2022
• Primary Completion: December 31, 2025
• Study Completion (Estimated): May 31, 2026
• Last Updated: August 28, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)