Inguinal and Axillary LN Size Distribution

NCT06559202 | Completed

• 1 other identifier: GDIRB2024-098
• Study Type: observational
• Target: 133
• Locations: 1 country
• Sites: 1

Brief Summary

Recently, intralymphatic allergen-specific immunotherapy (ILIT) showed promising treatment outcomes for allergic rhinoconjunctivitis. However, the normal size distribution of superficial lymph nodes (LNs) on the trunk that are potential target LNs for ILIT has not been evaluated. The objective of this study is to investigate the distribution of LN size in inguinal and axillary area.

Conditions

Lymph Nodes

Keywords

lymph nodes; immunotherapy; intralymphatic immunotherapy; computed tomography

Outcome Measures

Primary Outcomes (2)

• Inguinal LN size

  The long-axis diameter of the largest inguinal lymph node

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

• Axillary LN size

  The long-axis diameter of the largest axillary lymph node

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

Secondary Outcomes (2)

• Subjects with inguinal LN size ≥ 10mm

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

• Subjects with axillary LN size ≥ 10mm

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

Other Outcomes (9)

• Correlation between inguinal and axillary LN sizes

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

• Correlation between inguinal LN size and age

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

• Correlation between axillary LN size and age

  On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022

Study Arms (1)

CT group

Participants who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes

Diagnostic Test: chest and abdominoplevic CT

Interventions

chest and abdominoplevic CT DIAGNOSTIC_TEST

chest and abdominopelvic computed tomography on the same day for health screening purposes

CT group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

subjects who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes

You may qualify if:

• subjects who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes

You may not qualify if:

• Malignancy
• Follow-up less than 1-year

Sponsors & Collaborators

• Gachon University Gil Medical Center: lead
• Dankook University: collaborator

Study Sites (1)

Gachon University Gil Medical Center

Incheon, 21565, South Korea

Location

Study Officials

• So Hyun Park, MD, PhD

  Gachon University Gil Medical Center

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 10, 2024
• First Posted: August 19, 2024
• Study Start: September 2, 2022
• Primary Completion: November 30, 2022
• Study Completion: November 30, 2022
• Last Updated: August 19, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)