The Internal Prospective Validation of the Cancer Admission Score (CAS) Prediction Model

NCT06558487 | Recruiting

• 1 other identifier: 12821
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this single center prospective observational study is to determine the agreement between the cancer admission score (CAS) predicted disposition and the actual disposition in patients with an active cancer diagnosis visiting the emergency department (ED). The main question it aims to answer are: Is the performance of the CAS good enough to play a potential role in the ED care process. For each participant the CAS will be calculated and compared to the actual outcome.

Conditions

Oncology

Keywords

cancer care; emergency care; prediction model; admission

Outcome Measures

Primary Outcomes (3)

• Cancer Admission Score

  Cancer Admission Score (CAS) calculated after triage and after first blood results, ranging from 0 to 100%. The higher the score the greater the change of admission

  Through study completion, an average of 6 months

• Disposition

  The outcome of a visit to the ED, being either admission or home

  Through study completion, an average of 6 months

• Agreement between the CAS and the actual disposition

  Agreement between the CAS predicted outcome and the actual outcome

  Through study completion, an average of 6 months

Secondary Outcomes (4)

• Agreement between expected disposition by nurse and actual disposition

  Through study completion, an average of 6 months

• time-to-disposition

  Through study completion, an average of 6 months

• time-to-leave

  Through study completion, an average of 6 months

• ED Length of Stay

  Through study completion, an average of 6 months

Other Outcomes (7)

• Sex

  Through study completion, an average of 6 months

• Age

  Through study completion, an average of 6 months

• Type of Cancer

  Through study completion, an average of 6 months

Study Arms (1)

Cancer patients

All adult patients with an active cancer diagnosis who visit the emergency department (ED) of the Erasmus University Medical Centre (Erasmus MC).

Other: Cancer Admission Score Prediction Model

Interventions

Cancer Admission Score Prediction Model OTHER

A prediction model that calculates the chance for a patient to be admitted after triage and after first blood results

Cancer patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adult patients with an active cancer diagnosis who visit the ED of the Erasmus University Medical Center (Erasmus MC).

You may qualify if:

• Patients with solid or hematological malignancies and receiving systemic therapy or having received systemic therapy within the last 3 months.
• Presented at or admitted from the emergency department for the oncology, hematology neuro- or lung-oncology clinical unit.

You may not qualify if:

• \<18 years old
• Only received a surgical intervention as cancer treatment
• Admitted to the ED for the surgical department

Sponsors & Collaborators

• Erasmus Medical Center: lead

Study Sites (1)

Erasmus University Medical Center

Rotterdam, South Holland, 3015GD, Netherlands

RECRUITING

MeSH Terms

Conditions

Neoplasms

Study Officials

• Jason den Duijn

  Erasmus Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jason den Duijn

CONTACT

0107040704; j.denduijn@erasmusmc.nl

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 14, 2024
• First Posted: August 16, 2024
• Study Start: December 2, 2024
• Primary Completion: December 1, 2025
• Study Completion: December 31, 2025
• Last Updated: August 15, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

NL (1)