NCT06699615

Brief Summary

The objective of this proposal is to conduct a vignette-based survey among practicing oncology clinicians who treat non-small cell lung cancer to assess the trustworthiness of explainable predictions from a neurosymbolic AI vs. State-of-the-art post-hoc explanatory algorithms, using simulated patient data.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2024

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 19, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 21, 2024

Completed
11 days until next milestone

Study Start

First participant enrolled

December 2, 2024

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 15, 2026

Completed
Last Updated

July 18, 2025

Status Verified

January 1, 2025

Enrollment Period

1.4 years

First QC Date

November 19, 2024

Last Update Submit

July 16, 2025

Conditions

Oncology

Outcome Measures

Primary Outcomes (1)

  • Determine whether neurosymbolic AI explainability methods improve the trustworthiness of explanations from a prognostic model, relative to post-hoc explainers.

    Oncologist will be invited to complete a vignette-based survey

    3 months

Study Arms (1)

One time de-identified Qualtrics Survey

OTHER
Other: Once time de-identified Qualtrics survey

Interventions

Once time de-identified Qualtrics surveyOTHER

Once time de-identified Qualtrics survey

One time de-identified Qualtrics Survey

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may not qualify if:

  • Non-medical oncologists No email address or physical address listed Does not treat lung cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19083, United States

Location

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: Consented participants will complete a one time de-identified Qualtrics survey.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 19, 2024

First Posted

November 21, 2024

Study Start

December 2, 2024

Primary Completion

April 15, 2026

Study Completion

April 15, 2026

Last Updated

July 18, 2025

Record last verified: 2025-01

Locations

US(1)