TMJ Dysfunction: Effects on Proprioception, Pain, and Body Awareness

NCT06558318 | Completed

• 1 other identifier: AtılımU
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The term "temporomandibular joint dysfunction" (TMJ dysfunction) refers to a range of anatomical and functional problems, with or without clinical signs and symptoms, that affect the TMJ and/or the chewing muscles. It is more frequent in women and young people ages between 20 and 40. Its frequency ranges from 28% to 88%. The term "temporomandibular joint dysfunction" (TMJ dysfunction) refers to a range of anatomical and functional problems, with or without clinical signs and symptoms, that affect the TMJ and/or the chewing muscles. It is more frequent in women and young people ages between 20 and 40. Its frequency ranges from 28% to 88%. This condition is frequently disregarded because of inadequate diagnosis . Additionally, TMJ dysfunction can particularly emerge in the early stages without the presence of pain. Due to the insidious onset of the disease, especially in the early stages, other TMJ-related factors, in addition to pain-related parameters, need to be considered.Therefore, the aim of the study is to investigate the effect of TME disorder on proprioception, body awareness, and pain-related parameters including pain threshold, pain tolerance, and temporal summation in young adults.

Conditions

Temporomandibular Joint Disorders; Temporomandibular Disorder

Keywords

Joint Position Sense; Quantitative Sensory Testing; Temporal summation; Cervical proprioception

Outcome Measures

Primary Outcomes (2)

• Proprioception Assessment-1 (self-reported)

  Evaluation of proprioception using the Fremantle Neck Awareness Questionnaire:Self-reported proprioception will be assessed using the Fremantle Neck Awareness Questionnaire. The Fremantle Neck Awareness Questionnaire (FreNAQ) typically consists of 9 items, each rated on a Likert scale from 0 to 4. The scale ranges from 0 to 36 points. Higher scores on this scale indicate impaired neck awareness.

  Single assessment at baseline

• Proprioception assessment-2

  Evaluation of proprioception with joint position sense measurement via a CROM device: Proprioception will also be assessed with joint position sense via a CROM device. After finding the target angle in right and left rotation directions, the patient is asked to repeat the target angle with their eyes closed. The difference is recorded. Three measurements are taken, and the average is calculated.

  Single assessment at baseline.

Secondary Outcomes (2)

• Pain-related parameters

  Single assessment at baseline.

• Assessment of body awareness

  Single assessment at baseline.

Study Arms (2)

"TMJ Dysfunction" for the group with TMJ dysfunction.

This group consists of young adults aged 18-25 who have been diagnosed with temporomandibular joint (TMJ) dysfunction. The diagnosis was determined using the Fonseca Amnestic Index, where participants with a score greater than 20 were classified into this group. The participants in this group are being analyzed for proprioception, body awareness, and pain-related parameters, including pain threshold, pain tolerance, and temporal summation.

Other: Assessment of temporomandibular dysfunction

"No TMJ Dysfunction" for the group without TMJ dysfunction.

This group includes young adults aged 18-25 who do not exhibit temporomandibular joint (TMJ) dysfunction. Participants in this group have a Fonseca Amnestic Index score of 20 or lower. Similar to the TMJ dysfunction group, these participants are being evaluated for proprioception, body awareness, and pain-related parameters such as pain threshold, pain tolerance, and temporal summation.

Other: Assessment of temporomandibular dysfunction

Interventions

Assessment of temporomandibular dysfunction OTHER

TMJ dysfunction will be measured using the Fonseca Amnestic Index. The Fonseca Amnestic Index is used to assess the severity of temporomandibular joint (TMJ) dysfunction. The index consists of 10 questions, with each question scored as 0, 5, or 10 points, depending on the severity of symptoms. The maximum total score is 100, where a higher score indicates a more severe level of TMJ dysfunction. Therefore, patients with higher scores on the Fonseca Amnestic Index are considered to have more significant TMJ issues. Based on Fonseca scores, two groups will be formed: those with scores over 20 will be labeled 'with TMJ dysfunction,' and the others 'without TMJ dysfunction.

"No TMJ Dysfunction" for the group without TMJ dysfunction.; "TMJ Dysfunction" for the group with TMJ dysfunction.

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of young adults aged 18-25, including those with temporomandibular joint (TMJ) dysfunction and asymptomatic controls without TMJ dysfunction. Participants are recruited from Atılım University.

You may qualify if:

• \*Being between 18-25 years old

You may not qualify if:

• History of cervical spine injuries or disorders
• Chronic pain conditions or diagnosed musculoskeletal disorders
• Previous neck or spine surgeries
• Neurological or psychiatric conditions affecting proprioception or pain perception
• Use of medications influencing pain sensitivity or proprioception
• Pregnancy

Sponsors & Collaborators

• Nagihan Acet: lead

Study Sites (1)

Atılım University

Ankara, Ankara, 06560, Turkey (Türkiye)

Location

Related Publications (13)

• Shen S, Ye M, Wu M, Zhou W, Xu S. MRI and DC/TMD Methods Analyze the Diagnostic Accuracy of the Change in Articular Disc of Temporomandibular Joint. Comput Math Methods Med. 2022 Feb 15;2022:1770810. doi: 10.1155/2022/1770810. eCollection 2022.

  PMID: 35211184 RESULT

• Ohrbach R, Dworkin SF. The Evolution of TMD Diagnosis: Past, Present, Future. J Dent Res. 2016 Sep;95(10):1093-101. doi: 10.1177/0022034516653922. Epub 2016 Jun 16.

  PMID: 27313164 RESULT

• Türken, R., S.K. Büyük, and Y. Yasin, Diş Hekimliği Fakültesi Öğrencilerinde Temporomandibular Eklem Rahatsızlıklarının ve Ağız Sağlığı Alışkanlıklarının Değerlendirilmesi. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 2020(2): p. 208-213.

  RESULT

• Pires PF, de Castro EM, Pelai EB, de Arruda ABC, Rodrigues-Bigaton D. Analysis of the accuracy and reliability of the Short-Form Fonseca Anamnestic Index in the diagnosis of myogenous temporomandibular disorder in women. Braz J Phys Ther. 2018 Jul-Aug;22(4):276-282. doi: 10.1016/j.bjpt.2018.02.003. Epub 2018 Feb 21.

  PMID: 29519746 RESULT

• Heisler AC, Song J, Dunlop DD, Wohlfahrt A, Bingham CO III, Bolster MB, Clauw DJ, Marder W, Phillips K, Neogi T, Lee YC. Association of Pain Centralization and Patient-Reported Pain in Active Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2020 Aug;72(8):1122-1129. doi: 10.1002/acr.23994. Epub 2020 Jul 21.

  PMID: 31162824 RESULT

• Revel M, Andre-Deshays C, Minguet M. Cervicocephalic kinesthetic sensibility in patients with cervical pain. Arch Phys Med Rehabil. 1991 Apr;72(5):288-91.

  PMID: 2009044 RESULT

• Peng B, Yang L, Li Y, Liu T, Liu Y. Cervical Proprioception Impairment in Neck Pain-Pathophysiology, Clinical Evaluation, and Management: A Narrative Review. Pain Ther. 2021 Jun;10(1):143-164. doi: 10.1007/s40122-020-00230-z. Epub 2021 Jan 12.

  PMID: 33464539 RESULT

• Mehling WE, Gopisetty V, Daubenmier J, Price CJ, Hecht FM, Stewart A. Body awareness: construct and self-report measures. PLoS One. 2009;4(5):e5614. doi: 10.1371/journal.pone.0005614. Epub 2009 May 19.

  PMID: 19440300 RESULT

• Law EY, Chiu TT. Measurement of cervical range of motion (CROM) by electronic CROM goniometer: a test of reliability and validity. J Back Musculoskelet Rehabil. 2013;26(2):141-8. doi: 10.3233/BMR-2012-00358.

  PMID: 23640315 RESULT

• Walton DM, Macdermid JC, Nielson W, Teasell RW, Chiasson M, Brown L. Reliability, standard error, and minimum detectable change of clinical pressure pain threshold testing in people with and without acute neck pain. J Orthop Sports Phys Ther. 2011 Sep;41(9):644-50. doi: 10.2519/jospt.2011.3666. Epub 2011 Sep 1.

  PMID: 21885906 RESULT

• Karaca, S. (2017). Vücut Farkındalığı Anketinin Türkçe uyarlaması: Geçerlik ve güvenirlik çalışması (Yayınlanmamış yüksek lisans tezi). Muğla Sıtkı Koçman Üniversitesi Sağlık Bilimleri Enstitüsü, Muğla.

  RESULT

• Onan D, Gokmen D, Ulger O. The Fremantle Neck Awareness Questionnaire in Chronic Neck Pain Patients: Turkish Version, Validity and Reliability Study. Spine (Phila Pa 1976). 2020 Feb 1;45(3):E163-E169. doi: 10.1097/BRS.0000000000003207.

  PMID: 31425430 RESULT

• World Health Organization. Oral Health SurveysBasic Methods. 4th ed. Geneva: World Health Organization; 1997. [

  RESULT

MeSH Terms

Conditions

Temporomandibular Joint Disorders

Condition Hierarchy (Ancestors)

Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Stomatognathic Diseases

Study Officials

• Nagihan Acet, Phd.

  Atılım University

  STUDY DIRECTOR

• Sena Nur Begen, MSc.

  Atılım University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Asst. Prof.

Study Record Dates

• First Submitted: August 14, 2024
• First Posted: August 16, 2024
• Study Start: August 19, 2024
• Primary Completion: December 19, 2024
• Study Completion: January 19, 2025
• Last Updated: November 25, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)