Interest of Bone Scintigraphy in the Search for Scaphotrapezoidal Osteoarthritis

NCT06555250 | Completed

• 1 other identifier: 29BRC21.0207 - PSR
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Rhizarthosis can be treated by prothesis of the carpo-metacarpal (CM) joint of the thumb. But, if the scaphotrapeziotrapezoid (STT) joint is also affected by arthrosis, treating the CM joint exclusively may result in partial pain relief. Thus, bone scintigraphy could identify early arthrosis of the STT joint when its appearance seems to be normal on planar radiography, suggesting another surgical procedure.

Conditions

Rhizarthrosis; Prosthesis Failure

Keywords

rhizarthrosis; bone scintigraphy

Outcome Measures

Primary Outcomes (1)

• Search for a statistically significant association between scintigraphic STT hyperfixation and residual pain after TM prosthesis for patients with no radiographically obvious STT involvement.

  STT scintigraphic hyperfixation and pain before surgery and 4 months after TM arthroplasty

  before surgery and 4 month after surgery

Secondary Outcomes (2)

• Search for an association between scintigraphic STT hyperfixation in quantitative analysis and residual pain after TM prosthesis for patients without advanced STT involvement on radiography.

  before surgery

• Assessing the involvement of other carpal joint compartments

  before surgery

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patient who beneficiate of a bone scintigraphy before arthroplasty for rhizarthrosis with failure medical treatment, without osteoarthritis of the STT joint on planar radiography

You may qualify if:

• failure of medical treatment of rhizarthrosis
• eligibility for prothesis
• no osteoarthritis of the STT joint on planar radiography
• no opposition from the patient

You may not qualify if:

• Refusal by a patient

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (1)

CHU de Brest

Brest, 29609, France

Location

MeSH Terms

Conditions

Prosthesis Failure

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 4, 2022
• First Posted: August 15, 2024
• Study Start: June 15, 2021
• Primary Completion: June 1, 2023
• Study Completion: October 31, 2023
• Last Updated: August 15, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: Data will be available after the publication of result and ending five years maximum following the last visit of the last patient
• Access Criteria: Data access requests will be reviewed by the internal committee of Brest UH. requestors will be required to sign and complete a data access agreement

Locations

FR (1)