The Diagnostic Power Of Coronary CT Angiography In Patients With Chest Pain And Zero Calcium Score

NCT06552663 | Not Yet Recruiting

• 1 other identifier: Coronary CT Angiography
• Study Type: observational
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

To prove the non-used wide diagnostic range of CCTA in diagnosis of other causes of chest pain in addition to the traditional known role in coronary atherosclerosis.

Conditions

CT - Coronary Thrombosis

Outcome Measures

Primary Outcomes (1)

• Evaluate outcome of coronary CT angiography in cases with chest pain with zero calcium score . Evaluate outcome of coronary CT angiography in cases with chest pain with zero calcium score . Evaluate outcome of coronary CT angiography

  Evaluate outcome of coronary CT angiography in cases with chest pain with zero calcium score

  two years

Interventions

CCTA DEVICE

Coronary CT angiography

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

* community sample * primary care clinic

You may qualify if:

• patients with chest pain whom are referred by cardiologist for coronary CT angiography and coronary artery calcium score to detect atherosclerosis .

You may not qualify if:

• Patients who refuse to sign the consent
• Subjects suspected of having myocardial infarction, unstable angina pectoris, or coronary artery disease
• Subjects who experienced heart attack within 40 days prior to the CT scan
• Subjects with a diagnosed complicated heart anomaly
• BMI \> 35 kg/m2
• Serum creatinine ≥ 1.5 mg/dl
• Pregnant subjects
• Subjects with a history of hypersensitivity reaction to contrast agents
• Subjects with contraindications to the use of nitroglycerine
• Subjects who plan to participate or enroll in other randomized clinical trials for cardiovascular disease.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (5)

• Buckberg GD, Nanda NC, Nguyen C, Kocica MJ. What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions. J Cardiovasc Dev Dis. 2018 Jun 4;5(2):33. doi: 10.3390/jcdd5020033.

  PMID: 29867011 BACKGROUND

• Villa AD, Sammut E, Nair A, Rajani R, Bonamini R, Chiribiri A. Coronary artery anomalies overview: The normal and the abnormal. World J Radiol. 2016 Jun 28;8(6):537-55. doi: 10.4329/wjr.v8.i6.537.

  PMID: 27358682 BACKGROUND

• Lusis AJ. Atherosclerosis. Nature. 2000 Sep 14;407(6801):233-41. doi: 10.1038/35025203.

  PMID: 11001066 BACKGROUND

• Nelson AJ, Ardissino M, Psaltis PJ. Current approach to the diagnosis of atherosclerotic coronary artery disease: more questions than answers. Ther Adv Chronic Dis. 2019 Nov 1;10:2040622319884819. doi: 10.1177/2040622319884819. eCollection 2019.

  PMID: 31700595 BACKGROUND

• Doris M, Newby DE. Coronary CT Angiography as a Diagnostic and Prognostic Tool: Perspectives from the SCOT-HEART Trial. Curr Cardiol Rep. 2016 Feb;18(2):18. doi: 10.1007/s11886-015-0695-4.

  PMID: 26782999 BACKGROUND

MeSH Terms

Conditions

Coronary Thrombosis

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Thrombosis; Embolism and Thrombosis; Vascular Diseases

Central Study Contacts

Mohamed A farrag, resident

CONTACT

01014849980; lithimohamed@gmail.com

hamdy M ibrahim, Professor

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Doctor

Study Record Dates

• First Submitted: August 10, 2024
• First Posted: August 14, 2024
• Study Start: September 1, 2024
• Primary Completion: September 1, 2025
• Study Completion: December 1, 2025
• Last Updated: August 14, 2024

Record last verified: 2024-08