Follow-up of the Systemic Lupus Erythematosus Cohort as Part of the Multidisciplinary Consultation at Brest CHRU

NCT06551389 | Recruiting

• 1 other identifier: COLUPUS (2017.CE.10)
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Systemic lupus erythematosus is a complex systemicautoimmune disease that can affect most organs of the human body. Although they are many recommendations on the diagnosis and managment of SLE, diagnosis and therapeutic managment is still challenging. A pluridisciplinary consultation grouping rheumatologist, nephrologist, dermatologist, gynecologist, internist and immunologists has been set up in 2009 at the university hospital of Brest. The investigators would like to identify in a longitudinal cohort the occurrence of the different clinico-biological and immunological patterns of systemic lupus erythematosus patients during our multidisciplinary consultation. It is now crucial to organize a standardized data collection of these patients in order to evaluate our pratices, to be able to study the epidemiology of SLE in our city, and to promote this initiative at national and international level.

Conditions

Systemic Lupus Erythematosus

Keywords

autoimmune diseases; joint diseases; cutaneous systemic diseases; musculoskeletal diseases; arthritis; rheumatoid; rheumatic diseases; connectivite tissue diseases; immune system diseases

Outcome Measures

Primary Outcomes (3)

• Cohort data

  Prevalence and incidence of the clinico-biological and immunological patterns in a longitudinal cohort present in the standardized collection book including evaluation of différents criteria aspects : SLICC criteria

  one year

• Cohort data

  Prevalence and incidence of the clinico-biological and immunological patterns in a longitudinal cohort present in the standardized collection book including evaluation of différents criteria aspects : SLEDAI score

  one year

• Cohort data

  Prevalence and incidence of the clinico-biological and immunological patterns in a longitudinal cohort present in the standardized collection book including evaluation of différents criteria aspects : SDI score

  one year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients of the systemic lupus erythematous's multidisciplinary consultation at Brest CHRU

You may qualify if:

• Any patient over 18 years old of the multidisciplinary consultation

You may not qualify if:

• Opposition of patient

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (1)

CHRU de Brest

Brest, 29609, France

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

Biosamples in routine

MeSH Terms

Conditions

Lupus Erythematosus, Systemic; Autoimmune Diseases; Joint Diseases; Musculoskeletal Diseases; Arthritis; Rheumatic Diseases; Immune System Diseases

Condition Hierarchy (Ancestors)

Connective Tissue Diseases; Skin and Connective Tissue Diseases

Central Study Contacts

Sandrine JOUSSE-JOULIN, Rheumatologist

CONTACT

33 (0)2-98-34-72-64; sandrine.jousse-joulin@chu-brest.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2019
• First Posted: August 13, 2024
• Study Start: October 13, 2020
• Primary Completion (Estimated): April 1, 2035
• Study Completion (Estimated): April 1, 2035
• Last Updated: June 25, 2026

Record last verified: 2026-06

Locations

FR (1)