Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazil

NCT06548893 | Active Not Recruiting DMC

• 1 other identifier: 61795622.3.0000.0096
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) + Exposure and Response Prevention (ERP) in Group is effective to Obsessive Compulsive Disorder (OCD) in adults. Researchers will compare intervention to control group to see if those who attend the group therapy have better results than control group. Participants will go through a 16-week group therapy based on a protocol designed by Michael Twohig (Twohig et al, 2018).

• Participants will not have any medication adjustment during therapy
• Participants will be assessed 3 times throughout the therapy, plus an assessment in a 6-month follow-up.

Conditions

Obsessive-Compulsive Disorder

Keywords

OCD; Obsessive-compulsive disorder

Outcome Measures

Primary Outcomes (1)

• Yale-Brown Obsessive-Compulsive Scale (YBOCS)

  Measure for assessing the presence and severity of obsessive-compulsive disorder (OCD) symptoms.

  10 months (4-month intervention + 6-month follow-up)

Secondary Outcomes (6)

• Acceptance and Commitment Therapy Processes (CompACT)

  10 months (4-month intervention + 6-month follow-up)

• Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-SV)

  10 months (4-month intervention + 6-month follow-up)

• Depression Anxiety and Stress Scale (DASS)

  10 months (4-month intervention + 6-month follow-up)

• AAQ for Obsessions and Compulsions (AAQ-OC)

  10 months (4-month intervention + 6-month follow-up)

• Affective Style Questionnaire (ASQ)

  10 months (4-month intervention + 6-month follow-up)

Study Arms (2)

Group psychotherapy with ACT

EXPERIMENTAL

16 sessions of group psychotherapy based on ACT + exposure with response prevention (EPR)

Other: Group acceptance and commitment therapy (ACT)

Treatment as usual

NO INTERVENTION

Patients will follow their usual treatment, without adding ACT-based group psychotherapy

Interventions

Group acceptance and commitment therapy (ACT) OTHER

Group psychotherapy based on ACT + EPR

Also known as: Group Psychotherapy, Acceptance and Commitment Therapy, Psychotherapy

Group psychotherapy with ACT

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• OCD diagnosis according to DMS-5/ Minimum score of 20 in YBOCS

You may not qualify if:

• Psychotic disorder, maniac episode, intellectual disability, Chemical dependency, Suicidal risk, another current psychotherapy

Sponsors & Collaborators

• Universidade Federal do Paraná: lead

Study Sites (1)

Universidade Federal Do Paraná

Curitiba, Paraná, 80060-900, Brazil

Location

Related Publications (1)

• Twohig MP, Abramowitz JS, Smith BM, Fabricant LE, Jacoby RJ, Morrison KL, Bluett EJ, Reuman L, Blakey SM, Ledermann T. Adding acceptance and commitment therapy to exposure and response prevention for obsessive-compulsive disorder: A randomized controlled trial. Behav Res Ther. 2018 Sep;108:1-9. doi: 10.1016/j.brat.2018.06.005. Epub 2018 Jun 22.

  PMID: 29966992 BACKGROUND

Related Links

• ACT+ERP for OCD: This is a 16-session twice-weekly therapist manual for OCD describing ERP conducted from an ACT framework.

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Psychotherapy, Group; Acceptance and Commitment Therapy; Psychotherapy

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Socioenvironmental Therapy; Behavioral Disciplines and Activities; Cognitive Behavioral Therapy; Behavior Therapy

Study Officials

• Gabriela M Ferreira, MD, PhD

  Universidade Federal do Paraná

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Only the team member who will apply the questionnaires/scales will be masked.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ms

Model Details: Randomized controlled trial

Study Record Dates

• First Submitted: August 8, 2024
• First Posted: August 12, 2024
• Study Start: August 10, 2022
• Primary Completion: June 20, 2025
• Study Completion (Estimated): June 20, 2026
• Last Updated: August 12, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)