NCT06544629

Brief Summary

Based on the re-review of new drugs article, Korean pharmaceutical act, the objectives of this study are to assess safety and effectiveness of the study drugs(Imjudo \& Imfinzi) in a real world setting in patients who treated according to the approved indications in Korea.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
246

participants targeted

Target at P75+ for all trials

Timeline
34mo left

Started Apr 2025

Longer than P75 for all trials

Geographic Reach
1 country

6 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress28%
Apr 2025Feb 2029

First Submitted

Initial submission to the registry

August 6, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 9, 2024

Completed
8 months until next milestone

Study Start

First participant enrolled

April 14, 2025

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2029

Last Updated

November 21, 2025

Status Verified

November 1, 2025

Enrollment Period

3.9 years

First QC Date

August 6, 2024

Last Update Submit

November 20, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Safety (adverse events (AEs), serious AEs (SAEs), adverse drug reactions (ADRs), serious ADRs (SADRs), unexpected AEs/ADRs)

    To assess safety of the study drugs for patients treated with the study drugs under the approved indication in Korea

    For Imjudo will be conducted for 90 days from the first dose of the treatment. For Imfinzi will be separately conducted for 1 year from the first dose.

Secondary Outcomes (1)

  • Objective Response Rate(ORR)

    For 1 year from the first dose of the treatment

Other Outcomes (1)

  • Disease Control Rate (DCR)

    For 1 year from the first dose of the treatment

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who initiate treatment with study drugs after the contract date for the first time.

You may qualify if:

  • Patients eligible for the study drugs according to the approved label in Korea
  • Provision of signed and dated written informed consent by the patient or legally acceptable representative

You may not qualify if:

  • Other off-label indications according to the approved label in South Korea
  • Current participation in any interventional trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Research Site

Busan, South Korea

RECRUITING

Research Site

Goyang, South Korea

RECRUITING

Research Site

Seongnam, South Korea

RECRUITING

Research Site

Seoul, South Korea

RECRUITING

Research Site

Seoul, South Korea

NOT YET RECRUITING

Research Site

Suwon, South Korea

RECRUITING

MeSH Terms

Conditions

Carcinoma, Hepatocellular

Condition Hierarchy (Ancestors)

AdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsLiver NeoplasmsDigestive System NeoplasmsNeoplasms by SiteDigestive System DiseasesLiver Diseases

Central Study Contacts

AstraZeneca Clinical Study Information Center

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 6, 2024

First Posted

August 9, 2024

Study Start

April 14, 2025

Primary Completion (Estimated)

February 28, 2029

Study Completion (Estimated)

February 28, 2029

Last Updated

November 21, 2025

Record last verified: 2025-11

Locations