Does the Phoenix Pediatric Sepsis Prognosis Prediction Scale Work

NCT06539884 | Completed DMC

• 1 other identifier: TBAEK-391
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 2

Brief Summary

The aim of this study to understand the compatibility of Phoenix Score, International 2005 SIRS criterias and PRISM III, PELOD scoring systems. Defining pediatric sepsis in our research, epidemiology, scoring systems and prognosis. In addition, we will evaluate the advantages and disadvantages of the Phoenix criteria and assess the compatibility in pediatric sepsis scoring systems. The subject of our research is the use of the Phoenix criteria for pediatric sepsis. The aim of this study was to evaluate whether the 2005 SIRS - Sepsis diagnostic and grading criteria, pSOFA, PRISM III and PELOD scores are compatible and to compare their prognostic predictive power. The study is a 1-year prospective observational study. Patients will not undergo any interventional procedure or blood tests due to this study. No intervention will be made in the treatment protocol. In this study, Akdeniz University medical patients admitted to the Faculty of Pediatric Emergency Department with clinical sepsis suspicion will be included in the study. In 2024 it was aimed to evaluate whether the Phoenix criteria, which are recommended to be used to evaluate the prognosis of sepsis in pediatric patients, are compatible with the 2005 SIRS sepsis diagnosis and grading criteria, pSOFA, PRISM III and PELOD scores, which were widely used for this purpose in previous years and described in detail in the introduction section, and to compare their predictive power in terms of morbidity and mortality.

Conditions

Sepsis; Sepsis, Severe

Keywords

Phoenix Score; 2005 SIRS (systemic inflammatory response syndrome); PRISM III (Pediatric Mortality Risk Score); PELOD II (Pediatric Logistic Organ Dysfunction); pSOFA (Pediatric sequential organ failure assessment)

Outcome Measures

Primary Outcomes (1)

• Phoenix sepsis score correlates with length of stay in pediatric intensive care unit, length of stay in hospital, and mortality.

  Phoenix sepsis score correlates with length of stay in pediatric intensive care unit, length of stay in hospital, and mortality.

  1.5 year

Secondary Outcomes (6)

• SOFA score correlates with length of stay in pediatric intensive care unit, length of stay in hospital, and mortality.

  1,5 year

• Phoenix sepsis score, SOFA score, and 2005 SIRS -sepsis definition define all children with sepsis.

  1,5 years

• Phoenix sepsis score correlates with PRISM III, PELOD II scores, and the highest VIS observed during hospitalization.

  1,5 years

• SOFA score correlates with PRISM III, PELOD II scores, and the highest VIS observed during hospitalization.

  1,5 years

• Phoenix sepsis score correlates with FSS calculated at discharge.

  1,5 years

Interventions

Observational OTHER

Evaluating whether the 2005 SIRS - Sepsis diagnostic and grading criteria, pSOFA, PRISM III and PELOD scores are compatible and to compare their prognostic predictive power.

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All patients aged 1 month to 18 years with clinically suspected sepsis will be included in the study.

You may qualify if:

• Patients aged between 1 month to 18 years.
• Patients shall be suspected with sepsis clinically.

You may not qualify if:

• Patients under 1 month of age.
• Patients over 18 years of age.
• Patients have not diagnostics of sepsis

Sponsors & Collaborators

• Oguz Dursun: lead

Study Sites (2)

Akdeniz University

Antalya, Antalya, Turkey (Türkiye)

Location

Akdeniz University

Konyaalti, Antalya, 07100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Sepsis; Systemic Inflammatory Response Syndrome

Interventions

Watchful Waiting

Condition Hierarchy (Ancestors)

Infections; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Shock

Intervention Hierarchy (Ancestors)

Outcome Assessment, Health Care; Outcome and Process Assessment, Health Care; Quality of Health Care; Health Services Administration

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Prof. Dr.

Study Record Dates

• First Submitted: August 2, 2024
• First Posted: August 6, 2024
• Study Start: September 3, 2024
• Primary Completion: August 1, 2025
• Study Completion: October 1, 2025
• Last Updated: October 2, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)