Assessment of Human Exposure to Chemical Hazards

NCT06526169 | Active Not Recruiting

• 1 other identifier: NUS-IRB-2024-128
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 2

Brief Summary

The aim of this study is to evaluate the occurrence of chemical hazards exposure in the Singapore population and assess their association with food consumption.

Conditions

Dietary Exposure

Outcome Measures

Primary Outcomes (1)

• Chemical hazards occurrence

  To evaluate the occurrence of chemical hazards exposure in the Singapore population and assess their association with food consumption.

  3 years

Study Arms (3)

Ethnicity: Chinese

Other: Food Frequency, Social, Lifestyle, Demographic Questionnaires and Blood Collection

Ethnicity: Malay

Other: Food Frequency, Social, Lifestyle, Demographic Questionnaires and Blood Collection

Ethnicity: Indian

Other: Food Frequency, Social, Lifestyle, Demographic Questionnaires and Blood Collection

Interventions

Food Frequency, Social, Lifestyle, Demographic Questionnaires and Blood Collection OTHER

Questionnaires on food frequency, social, lifestyle, and demographics will be administered to participants and will be correlated with the presence of chemical hazards in the blood. The chemical hazards analyzed will be referenced from Singapore's Total Diet Study, based on the prioritized chemical hazards of interest to investigate the distribution of risk in the population.

Ethnicity: Chinese; Ethnicity: Indian; Ethnicity: Malay

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Healthy adults in the Singapore population

You may qualify if:

• Must be English-literate and able to give informed consent in English
• to 60 years of age (inclusive) at screening
• Healthy adults
• Race must be Chinese or Indian or Malay
• Reliable and willing to make themselves available for the duration of the study and are willing to follow study procedures

You may not qualify if:

• Known or ongoing psychiatric disorders within 3 years
• Being diagnosed with cancer, heart disease, stroke, renal failure, serious mental or physical illnesses at the time of recruitment
• Have donated blood of more than 500 mL within 4 weeks of study enrolment

Sponsors & Collaborators

• National University of Singapore: lead
• Singapore Food Agency: collaborator

Study Sites (2)

National University of Singapore

Singapore, 118177, Singapore

Location

National University of Singapore, Department of Food Science & Technology

Singapore, Singapore

Location

Biospecimen

Retention: SAMPLES WITH DNA

Plasma and serum samples

Study Officials

• Mei Hui Liu

  National University of Singapore

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Lecturer

Study Record Dates

• First Submitted: July 24, 2024
• First Posted: July 29, 2024
• Study Start: August 21, 2024
• Primary Completion (Estimated): July 31, 2027
• Study Completion (Estimated): July 31, 2027
• Last Updated: September 9, 2025

Record last verified: 2025-09

Locations

SG (2)