Pediatric Oncological Orthopaedic Reconstruction

NCT06522165 | Active Not Recruiting

• 1 other identifier: ROP
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

From the archives of the Rizzoli institute all the children undergoing oncological reconstruction from 1991 to 2023 (approximately 400 patients). A review will be made of the medical records, radiological imaging, and histological data of these patients

Conditions

Bone Tumor; Bone Cancer

Outcome Measures

Primary Outcomes (1)

• longevity of the reconstruction

  -assess the longevity associated with pediatric oncologic reconstructions;

  at baseline (day 0)

Secondary Outcomes (1)

• complications

  at baseline (day 0)

Study Arms (1)

patients

Male and female patients surgically treated with an oncological reconstructions at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2023

Other: Analysis

Interventions

Analysis OTHER

analysis and review of imaging and clinical data

patients

Eligibility Criteria

• Age: 2 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Male and female pediatric patients surgically treated with an oncological reconstruction from 1991 to 2023

You may qualify if:

• Diagnosis of bone sarcoma
• Patients with available clinical and imaging data

Sponsors & Collaborators

• Costantino Errani: lead

Study Sites (1)

IRCCS Itituto Ortopedico Rizzoli

Bologna, BO, 40136, Italy

Location

Related Publications (3)

• Abdeen A, Hoang BH, Athanasian EA, Morris CD, Boland PJ, Healey JH. Allograft-prosthesis composite reconstruction of the proximal part of the humerus: functional outcome and survivorship. J Bone Joint Surg Am. 2009 Oct;91(10):2406-15. doi: 10.2106/JBJS.H.00815.

  PMID: 19797576 BACKGROUND

• Aponte-Tinao LA, Ayerza MA, Muscolo DL, Farfalli GL. Allograft reconstruction for the treatment of musculoskeletal tumors of the upper extremity. Sarcoma. 2013;2013:925413. doi: 10.1155/2013/925413. Epub 2013 Feb 14.

  PMID: 23476115 BACKGROUND

• Azoury SC, Shammas RL, Othman S, Sergesketter A, Brigman BE, Nguyen JC, Arkader A, Weber KL, Erdmann D, Levin LS, Kovach SJ, Innocenti M. Outcomes following Free Fibula Physeal Transfer for Pediatric Proximal Humerus Reconstruction: An International Multi-Institutional Study. Plast Reconstr Surg. 2023 Apr 1;151(4):805-813. doi: 10.1097/PRS.0000000000010001. Epub 2022 Dec 6.

  PMID: 36729876 BACKGROUND

MeSH Terms

Conditions

Bone Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Bone Diseases; Musculoskeletal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 22, 2024
• First Posted: July 26, 2024
• Study Start: December 1, 2023
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: August 1, 2025

Record last verified: 2025-07

Locations

IT (1)