Proximal Femur Reconstruction Following Resection of Primary Bone Tumors: Analysis of the Clinical and Radiographic Results
ProFemuRe
1 other identifier
observational
150
1 country
1
Brief Summary
From the archives of the Rizzoli institute all the patients (approximately 150 patients) undergoing oncological reconstruction of proximal femur from 01/01/1991 to 31/12/2023. A review will be made from the medical records, radiological imaging, and histological data of these patients
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 29, 2024
CompletedFirst Submitted
Initial submission to the registry
June 27, 2024
CompletedFirst Posted
Study publicly available on registry
July 3, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2025
CompletedApril 1, 2025
March 1, 2025
1.6 years
June 27, 2024
March 26, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
longevity of the reconstruction
evaluation of the longevity of the reconstruction, meaning reconstruction failure-free survival after surgery
At baseline (Day 0)
Secondary Outcomes (1)
Musculoskeletal tumour society (MSTS) functional evaluation
at baseline (day 0)
Study Arms (1)
Patients
Male and female patients surgically treated with an oncological reconstruction of the proximal femur at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2023
Interventions
Eligibility Criteria
Male and female patients surgically treated with an oncological reconstruction of the proximal femur at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2023
You may qualify if:
- Male and female patients surgically treated with an oncological reconstruction of the proximal femur at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2023
- Age: 18-90 years old (at the time of primary surgery)
- Diagnosis of bone sarcoma
- Patients with available clinical and imaging data
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
IRCCS Itituto Ortopedico Rizzoli
Bologna, BO, 40136, Italy
Related Publications (2)
Tobey D, Wing C, Calkins T, Heck RK. The Use of Proximal Femur Replacement for the Management of Oncologic Lesions in the Proximal Femur: A Review. Orthop Clin North Am. 2023 Jan;54(1):23-35. doi: 10.1016/j.ocl.2022.08.006. Epub 2022 Oct 23.
PMID: 36402508BACKGROUNDMenendez LR, Ahlmann ER, Kermani C, Gotha H. Endoprosthetic reconstruction for neoplasms of the proximal femur. Clin Orthop Relat Res. 2006 Sep;450:46-51. doi: 10.1097/01.blo.0000229332.91158.05.
PMID: 16906093BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
June 27, 2024
First Posted
July 3, 2024
Study Start
April 29, 2024
Primary Completion
December 1, 2025
Study Completion
December 1, 2025
Last Updated
April 1, 2025
Record last verified: 2025-03