MAP( Mean Arterial Pressure) and Mortality Relation in Patients With Heart Failure

NCT06515366 | Recruiting

• 1 other identifier: MAP and Mortality
• Study Type: observational
• Target: 280
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of this observational study is to evaluate the relationship between mean arterial pressure (MAP) and mortality in patients presenting to the emergency department with acute heart failure, focusing on emergency department monitoring and subgroup presentations. Our goal is to determine the impact of subgroup characteristics on mortality among patients presenting with heart failure in the emergency department, and to assess the predictive value and significance of MAP in predicting mortality.

Conditions

Heart Failure

Keywords

heart failure; mean arterial pressure; emergency department

Outcome Measures

Primary Outcomes (1)

• mortality

  patients having mortaility within 1 month of follow up

  1 month

Secondary Outcomes (1)

• re-hospitalization

  1 month

Study Arms (4)

MAP ≤ 65 mmHg

patient having heart failure symptoms with known heart failure and presenting to emergency department with a mean arterial pressure ≤ 65 mmHg

MAP 66-80 mmHg

patient having heart failure symptoms with known heart failure and presenting to emergency department with a mean arterial pressure between 66-80 mmHg

MAP 81-100 mmHg

patient having heart failure symptoms with known heart failure and presenting to emergency department with a mean arterial pressure between 81-100 mmHg

MAP >100 mmHg

patient having heart failure symptoms with known heart failure and presenting to emergency department with a mean arterial pressure between \>100 mmHg

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients over the age of 18 with known heart failure, presenting to emergency department with acute exacerbation of heart failure symptoms will be grouped according to their measured mean arterial pressure (MAP)

You may qualify if:

• Age 18 and above Patients presenting with symptoms of heart failure

You may not qualify if:

• Age under 18 Patients presenting with ST-elevation myocardial infarction Patients with acute kidney failure Pregnant patients Patients with inaccessible data for the parameters under study

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead
• Ankara Etlik City Hospital: collaborator

Study Sites (1)

Etlik City Hospital

Ankara, Yenimahalle, 06170, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Ma H, Li H, Sheng S, Quan L, Yang Z, Xu F, Zeng W. Mean arterial pressure and mortality in patients with heart failure: a retrospective analysis of Zigong heart failure database. Blood Press Monit. 2023 Dec 1;28(6):343-350. doi: 10.1097/MBP.0000000000000674. Epub 2023 Sep 14.

  PMID: 37702595 BACKGROUND

• Burstein B, Tabi M, Barsness GW, Bell MR, Kashani K, Jentzer JC. Association between mean arterial pressure during the first 24 hours and hospital mortality in patients with cardiogenic shock. Crit Care. 2020 Aug 20;24(1):513. doi: 10.1186/s13054-020-03217-6.

  PMID: 32819421 BACKGROUND

• Gao Q, Lin Y, Xu R, Zhang Y, Luo F, Chen R, Li P, Nie S, Li Y, Su L. Association between mean arterial pressure and clinical outcomes among patients with heart failure. ESC Heart Fail. 2023 Aug;10(4):2362-2374. doi: 10.1002/ehf2.14401. Epub 2023 May 12.

  PMID: 37177860 BACKGROUND

MeSH Terms

Conditions

Heart Failure; Emergencies

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• gulsen akcay, ass. prof.

  ass. prof. of organization

  STUDY DIRECTOR

Central Study Contacts

gulsen akcay, ass. prof.

CONTACT

+905052874949; gulakcay@yahoo.com.tr

elif hamzacebioglu kayisoglu, specialist

CONTACT

+905453300679; turkuaz-61@windowslive.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 17, 2024
• First Posted: July 23, 2024
• Study Start: June 1, 2024
• Primary Completion: June 1, 2025
• Study Completion: June 1, 2025
• Last Updated: July 23, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)