Does Cervical Mobilization Have an Effect on Hand Function in Patients With Double Crush Syndrome?

NCT06493617 | Completed

• 1 other identifier: P.T.REC/012/003943
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

All Double Crush Syndrome patients were assessed via VAS, BCTQ \& Nerve conduction study before and after the treatment program.

Conditions

Double Crush Syndrome

Keywords

cervical mobilization; hand function; double crush syndrome

Outcome Measures

Primary Outcomes (3)

• Visual analogue scale

  Used to assess degree of pain

  4 weeks

• Boston carpal tunnel syndrome questionnaire

  Used to assess patients' functional ability and symptoms severity

  4 weeks

• Nerve conduction study

  Used to assess sensory and motor fibers of median nerve to determine the improvement in nerve capacity and hand function

  4 weeks

Study Arms (2)

Control Group

EXPERIMENTAL

received a standard physical therapy program of nerve glide, hand strengthening exercise and mobilization

Other: Traditional physical therapy treatment

Study Group

EXPERIMENTAL

received a cervical mobilization in addition to the standard physical therapy program for 12 sessions

Other: Cervical Mobilization; Other: Traditional physical therapy treatment

Interventions

Cervical Mobilization OTHER

The technique is used to mobilize a specific cervical or upper thoracic segment (C2-C3 through T3-T4) in a posterior to anterior direction. The therapist gently applies pressure in an anteroposterior direction in the plane of the facet joint to assess mobility, resistance, end feel, and pain provocation. Gentle oscillations can be used to either inhibit pain (grades I and II) or restore motion (grades III and IV). Slight variations in depth and direction of force can be used to optimize the therapeutic effects of this technique.

Study Group

Traditional physical therapy treatment OTHER

tendon gliding exercises, median nerve gliding exercise, strengthening exercises for 60 minutes

Control Group; Study Group

Eligibility Criteria

• Age: 25 Years - 35 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Thirty female patients diagnosed as Double Crush Syndrome based on the clinical diagnostic criteria of the American Academy of Neurology, (American Academy of Neurology 2019).
• Patient ages ranged from 25 to 35 years old. Patient who reported pain, hyperesthesia, and/or paresthesia at the course of median nerve distribution and upper limb.
• A Nerve Conduction Study (NCS) evidence of peripheral entrapment of median nerve at level of carpal bone "Carpal tunnel Syndrome" with a fractionated sensory nerve conduction velocity for the median nerve across the wrist of 40 m/s or less and with sensory peak latency \> 3.6 ms and recordable and with motor distal latency \>4.4 ms and less than 6.5ms.

You may not qualify if:

• Patients had Systemic disease causes double Crush Syndrome as rheumatoid arthritis (RA), thyroid disease, Diabetes mellitus (DM), Pregnant women, Patients with concomitant neurological disease as peripheral neuropathy, Patients with history of wrist surgery, fracture, or carpal tunnel injection in the last two weeks before the study, Patients who have wasting of the thenar muscles, Patients with previous surgery for CTS.
• Patients with complete conduction block on EDX or previous regular exposure to hand-held vibrating tools, Patients with Nerve Conduction Study with motor distal latency \> 6.5 ms.

Sponsors & Collaborators

• Ahmed Alshimy: lead

Study Sites (1)

Al Ryada University for Science and Technology

Sadat, Menoufia, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Lecturer of Physical Therapy for Neurology and it's Surgery

Study Record Dates

• First Submitted: July 2, 2024
• First Posted: July 10, 2024
• Study Start: August 2, 2022
• Primary Completion: August 5, 2023
• Study Completion: January 8, 2024
• Last Updated: July 12, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)