Studying the Effectiveness of Early Invasive Treatment in Elderly Patients With High-risk Non-ST-segment Elevation Acute Coronary Syndrome.

NCT06486233 | Recruiting

• 1 other identifier: 329/HDDD-DHYD
• Study Type: observational
• Target: 385
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this is observational study is to compare about MACE events and predisposing factors related to MACE events in elderly patients with high-risk non-ST acute coronary syndromes receiving early versus late invasive treatment . This study will anwser two questions. Question 1: What will factors associate with implementing a late invasive strategy in elderly patients with high-risk non-ST-segment elevation acute coronary syndrome ? Question 2: Is a meaningful difference about mortality and complication rates as re-myocardial infarction, heart failure, re-hospitalization, stroke after 12 months between two groups of patients undergoing early invasive and late invasive strategies in elderly patients with in high-risk non-ST-segment elevation acute coronary syndrome?

Conditions

Myocardial Infarction

Keywords

percutaneous coronary intervention, elderly, non-ST-segment Elevation

Outcome Measures

Primary Outcomes (1)

• In-hospital death

  recorded when death occurs during treatment or is confirmed by in-hospital monitoring

  one month

Secondary Outcomes (2)

• after 12 months death

  one year

• MACE after 12 months include re-admission, recurrent myocardial infarction , stroke, heart failure

  one year

Study Arms (2)

Observe the patient with early percutaneous coronary intervention

Elderly patients with non-ST-segment elevation acute coronary syndrome receive early percutaneous coronary intervention (\< 24 hours after diagnosis).

Observe the patient with late percutaneous coronary intervention

Elderly patients with non-ST elevation acute coronary syndrome undergoing late percutaneous coronary intervention (≥ 24 hours after diagnosis)

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients aged 60 years and older were diagnosed with non-ST elevation acute coronary syndrome. Diagnosed with high-risk acute non-ST elevation syndrome and treated at Gia Dinh People's Hospital, Thong Nhat Hospital during the study period.

You may qualify if:

• aged 60 years and older
• high - risk non-ST-segment elevation acute coronary syndrome (according to the 2023 European Heart Association recommended standards).
• receives reperfusion intervention.

You may not qualify if:

• Acute coronary syndrome due to stent thrombosis, or coronary artery bypass graft occlusion.
• Incomplete medical records.

Sponsors & Collaborators

• Gia Dinh People Hospital: lead

Study Sites (1)

Gia Dinh people hospital

Ho Chi Minh City, Vietnam

RECRUITING

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Central Study Contacts

Sang Thanh Nguyen, Doctor

CONTACT

+84902489252; drsangthanhnguyen@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 12, 2024
• First Posted: July 3, 2024
• Study Start: February 22, 2024
• Primary Completion: March 1, 2026
• Study Completion (Estimated): March 1, 2028
• Last Updated: July 3, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

VN (1)