Patients With Non-ST-segment Elevation Acute Coronary Syndrome

NCT05159973 | Completed

• 1 other identifier: 8410
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

There are two types of acute coronary syndrome (ACS): ACS with persistent ST segment elevation (ACS ST +) and ACS without ST segment elevation (non-ST + ACS). The incidence of non-ST + ACS is increasing and currently accounts for the majority of myocardial infarction (MI) hospitalizations, while that of ST + ACS is declining. Complications of MI, which include rhythm and conduction disturbances, are mainly associated with ACS ST +. It is recognized that these complications can occur during non-ST + ACS, but with less frequency. This frequency is not clearly established, and has been the subject of few studies. Recent studies in this direction suggest that the frequency of rhythmic complications is low during non-ST + ACS. However, the data collected concerns inter-hospital transport. The aim of the study is to estimate the frequency of occurrence of potentially fatal rhythmic complications in patients admitted to the emergency room and to the cardiology department for non-ST + ACS.

Conditions

Myocardial Infarction

Keywords

Acute Coronary Syndrome; ACS; ST segment elevation; Myocardial infarction

Outcome Measures

Primary Outcomes (1)

• Evaluation of the frequency of occurrence of potentially fatal rhythmic complications in patients with non-ST segment elevation acute coronary syndrome

  Files analysed retrospectively from January 01, 2019 to December 31, 2020 will be examined]

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient whose main diagnosis retained at the end of hospitalization is a non-ST + ACS

You may qualify if:

• Adult patient (≥ 18 years old)
• Man or woman
• Patient admitted to the Emergency Department (SU) or to the Cardiology Department at the NHC between January 1, 2019 and December 31, 2020
• Patient whose main diagnosis retained at the end of hospitalization is a non-ST + ACS
• Patient who did not express his opposition to the reuse of his data for scientific research purposes.

You may not qualify if:

• Subject having expressed opposition to participating in the study
• Subject under guardianship, curatorship or safeguard of justice

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service des Urgences Médico-Chirurgicales Adultes - Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Myocardial Infarction; Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• Sébastien HARSCOAT, MD

  Service des Urgences Médico-Chirurgicales Adultes - Hôpitaux Universitaires de Strasbourg

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2021
• First Posted: December 16, 2021
• Study Start: October 1, 2021
• Primary Completion: September 21, 2022
• Study Completion: September 21, 2022
• Last Updated: March 6, 2025

Record last verified: 2025-03

Locations

FR (1)