NCT06485310

Brief Summary

The goal of this clinal trial is to compare the effectiveness of nurse-led teleconsultation with usual care (intervention group) on psychological distress in patients with primary malignant tumors of the central nervous system between diagnosis and first anti-cancer treatment, versus usual care alone (control group). Participants will be randomized into two groups :

  • group A) intervention: usual care + nurse teleconsultation for psychological support
  • group B) control: usual care alone Enrolment = Day0 (D0) Participants will :
  • groups A and B: D0: complete 4 questionnaires (Quality of Life, Screening for Distress, Screening for Anxiety and Depression, Social Support Questionnaire)
  • Group A : D0+2/4 das : nursing teleconsultation for psychological support
  • Groups A and B: D0+10days : telephone call to complete the same 4 questionnaires as at inclusion
  • Group A : D0+15days: semi-directive interview, at home, for voluntary patients.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
26mo left

Started Mar 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress5%
Mar 2026Jun 2028

First Submitted

Initial submission to the registry

June 26, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 3, 2024

Completed
1.7 years until next milestone

Study Start

First participant enrolled

March 31, 2026

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2028

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

January 20, 2026

Status Verified

January 1, 2026

Enrollment Period

2 years

First QC Date

June 26, 2024

Last Update Submit

January 16, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Distress thermometer

    Comparison of the change in psychological distress score, measured using the psychological distress screening tool (from National Comprehensive Cancer Network) between the 2 groups between inclusion (T0) and before the first anti-cancer therapy (T1).

    10 days

Study Arms (2)

TELECONSULTATION

EXPERIMENTAL

Teleconsultation with a nurse for psychological support, after the diagnosis has been announced, before hospitalization for the first treatment (chemotherapy, surgery, radiotherapy) in addition to the standard practice.

Other: Teleconsultation for psychological support

NO TELECONSULTATION

NO INTERVENTION

The control group will be cared for according to standard practice (without teleconsultation)

Interventions

Teleconsultation with a nurse for psychological support, after the diagnosis has been announced, before hospitalization for the first treatment (chemotherapy, surgery, radiotherapy) in addition to the standard practice

TELECONSULTATION

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • aged 18 and over
  • being treated for a primary malignant tumor of the central nervous system (positive biopsy)
  • with a Mini-Mental State score greater than 24
  • not receiving first-line treatment (chemotherapy, targeted radiotherapy, surgery)
  • with a distress score above 3 on the Psychological Distress Thermometer
  • have access to computer equipment equipped with a microphone and webcam (smartphone, computer)
  • able to read, write and speak French
  • have given free and informed consent
  • being affiliated to a social security scheme

You may not qualify if:

  • with a history of psychiatric illness
  • with recurrent cancer of the cerebral nervous system
  • having begun first-line treatment (drug therapy, curative surgery, radiotherapy or palliative care)
  • under guardianship, curatorship or deprived of liberty

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital of Reunion Island - Neurosurgery department

Saint-Pierre-des-Corps, Reunion, 97410, France

Location

MeSH Terms

Conditions

Central Nervous System Neoplasms

Interventions

Remote Consultation

Condition Hierarchy (Ancestors)

Nervous System NeoplasmsNeoplasms by SiteNeoplasmsNervous System Diseases

Intervention Hierarchy (Ancestors)

Referral and ConsultationProfessional PracticeOrganization and AdministrationHealth Services AdministrationTelemedicineDelivery of Health CarePatient Care Management

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 26, 2024

First Posted

July 3, 2024

Study Start

March 31, 2026

Primary Completion (Estimated)

March 31, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

January 20, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations