NCT05971160

Brief Summary

The goal of this study is to test the ability of small grants and/or peer support to improve mental health among transgender people experiencing material hardship. The main questions the study will answer are:

  1. 1.Do microgrants with or without peer mentoring improve mental health?
  2. 2.Do microgrants with or without peer mentoring improve mental health by reducing material hardship and/or increasing a sense of community connection?

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
360

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 24, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

August 2, 2023

Completed
4 months until next milestone

Study Start

First participant enrolled

December 12, 2023

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 21, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 21, 2026

Completed
Last Updated

March 27, 2026

Status Verified

March 1, 2026

Enrollment Period

2.3 years

First QC Date

July 24, 2023

Last Update Submit

March 24, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in psychological distress, as measured by Kessler 6

    Kessler 6 is a 6-item scale with each item scored from 0-4 for a total score range from 0-24, with higher scores indicating greater psychological distress.

    Baseline, 6 months, 12 months

Secondary Outcomes (1)

  • Change in substance use, as measured by the Drug Abuse Screening Test (DAST-10)

    Baseline, 6 months, 12 months

Study Arms (3)

Usual Care

ACTIVE COMPARATOR

Monthly financial education videos and one-time microgrant

Behavioral: Financial education videosOther: Microgrant

Monthly microgrants

ACTIVE COMPARATOR

Monthly financial education videos and monthly microgrants

Behavioral: Financial education videosOther: Microgrant

Monthly microgrants plus peer mentoring

ACTIVE COMPARATOR

Monthly financial education videos, monthly microgrants, and peer mentoring support

Behavioral: Financial education videosOther: MicrograntBehavioral: Peer mentoring

Interventions

Peer mentoringBEHAVIORAL

One-on-one structured mentoring sessions with a trained peer

Monthly microgrants plus peer mentoring

Brief videos providing structured information on managing one's money

Monthly micrograntsMonthly microgrants plus peer mentoringUsual Care

$150 stipend

Monthly micrograntsMonthly microgrants plus peer mentoringUsual Care

Eligibility Criteria

Age18 Years+
Sexall(Gender-based eligibility)
Gender Eligibility DetailsGender different from sex assigned at birth
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age 18 years or older
  • gender identity different from sex assigned on original birth certificate
  • access to a mobile phone or email
  • score \> 0 on the material hardship index

You may not qualify if:

  • inability to provide informed consent in English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Duke University (online recruitment)

Durham, North Carolina, 27710, United States

Location

Related Publications (1)

  • Poteat TC, Reisner SL, Wirtz AL, Mayo-Wilson LJ, Brown C, Kornbluh W, Humphrey A, Perrin N. A Microfinance Intervention With or Without Peer Support to Improve Mental Health Among Transgender and Nonbinary Adults (the Creating Access to Resources and Economic Support Study): Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2024 Aug 26;13:e63656. doi: 10.2196/63656.

Study Officials

  • Tonia C. Poteat, PhD

    Duke University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 24, 2023

First Posted

August 2, 2023

Study Start

December 12, 2023

Primary Completion

March 21, 2026

Study Completion

March 21, 2026

Last Updated

March 27, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

The investigators plan to share data via one of the NIH repositories listed by the Trans-NIH BioMedical Informatics Coordinating Committee (BMIC). The final available dataset from this proposed research will include self-reported demographic, psychosocial, and behavioral data from quantitative surveys. No personal identifiers will be included with the final available dataset.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data will become available 12 months after publication of primary study findings.
Access Criteria
In accordance with the NIH Data Sharing Policy and Implementation Guidance, the investigators will make the data and supporting information available to users under a data-sharing agreement that provides for: (1) complete protection of human subjects training and a commitment to research ethics; (2) a commitment to using the data only for research purposes and not to identify an individual participant; (3) a commitment to securing the data using appropriate technology, and (4) a commitment to destroying or returning the data after analyses are completed.

Locations